The important role of 10344-42-0

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10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, belongs to pyridazine compound, is a common compound. Product Details of 10344-42-0In an article, once mentioned the new application about 10344-42-0.

Pesticidally active bi-or tricyclic heterocycles with sulphur-containing substituents, stereoisomers and tautomeric forms thereof that can be used as insecticides and can be prepared in a manner known per se.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3009 – PubChem

 

Discovery of 10344-42-0

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10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, belongs to pyridazine compound, is a common compound. Product Details of 10344-42-0In an article, once mentioned the new application about 10344-42-0.

Some new 3-(alkylsulfanyl)-7-chloro-1-phenyl-1H-pyridazino [4,3-e][1,3,4]thiadiazine were synthesized by treatment of the alkyl-2-phenylhydrazinecarbodithioates with 4-bromo-3,6-dichloropyridazine in alkaline acetonitrile. Orientation of the reaction has been determined by X-ray crystallography technique. The chlorine atom on the number 7 position of these products was replaced by secondary amines at reflux condition.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3021 – PubChem

 

More research is needed about 10344-42-0

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 10344-42-0, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 10344-42-0, in my other articles.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 10344-42-0, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, molecular formula is C4HBrCl2N2

Synthesis of new derivatives of 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines

New 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines were prepared and evaluated for inhibitory activity against soybean 15-lipoxygenase enzyme. These compounds were synthesized by the sequential treatment of 4-bromo-3,6-dichloropyridazine with 2-aminothiophenol and a secondary amine with the subsequent heterocyclization in the presence of sodium amide.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3018 – PubChem

 

Brief introduction of 4-Bromo-3,6-dichloropyridazine

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C4HBrCl2N2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 10344-42-0, in my other articles.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C4HBrCl2N2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, molecular formula is C4HBrCl2N2

TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS

1,2,4-triazolo[4,3-b]pyridazine derivatives, represented by wherein Z represents cyclobutyl, 1-methylcyclopentyl or pyrrolidin-1-yl, are selective ligands for GABA A receptors, in particular having high affinity for the alpha2 and/or alpha3 subunit thereof, are useful in the treatment of anxiety and convulsions.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C4HBrCl2N2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 10344-42-0, in my other articles.

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3015 – PubChem

 

New explortion of 4-Bromo-3,6-dichloropyridazine

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10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, belongs to pyridazine compound, is a common compound. Recommanded Product: 10344-42-0In an article, once mentioned the new application about 10344-42-0.

SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS

Substituted triazolo-pyridazine derivative compounds represented by wherein the variables are disclosed herein are selective ligands for GABA-A receptors, particularly for the alpha2 and/or alpha3 subunits.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3010 – PubChem

 

Extended knowledge of 4-Bromo-3,6-dichloropyridazine

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 10344-42-0, and how the biochemistry of the body works.Application of 10344-42-0

Application of 10344-42-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, molecular formula is C4HBrCl2N2. In a Patent£¬once mentioned of 10344-42-0

HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON’S DISEASE

The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease. Formula (I). In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 10344-42-0, and how the biochemistry of the body works.Application of 10344-42-0

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3012 – PubChem

 

Can You Really Do Chemisty Experiments About 10344-42-0

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Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 4-Bromo-3,6-dichloropyridazine, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 10344-42-0

TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS

1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-alkoxy moiety at the 6-position, are selective ligands for GABA Areceptors, in particular having high affinity for the alpha2 and/or alpha3 subunit thereof, are useful in the treatment of anxiety and convulsions.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3017 – PubChem

 

Analyzing the synthesis route of 10344-42-0

10344-42-0, The synthetic route of 10344-42-0 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.10344-42-0,4-Bromo-3,6-dichloropyridazine,as a common compound, the synthetic route is as follows.

c 3,6-Dichloro-4-(pyrrolidin-1-yl)pyridazine To a slurry of 4-bromo-3,6-dichloropyridazine (115 g, 0.51 mol) and potassium carbonate (209 g, 1.5 mol) in DMF (1) was added pyrrolidine (46 ml, 0.56 mol) at 0 C. with stirring. The mixture was allowed to warm to room temperature and then stirred under nitrogen overnight. Water (1.5) was added and the resultant slurry was filtered. The residue was washed thoroughly with water and diethyl ether, yielding the title compound (110 g, 100%) as a fine white powder. 1H NMR (250 MHz, CDCl3) delta2.03 (4H, m), 3.64 (4H, m), 6.46 (1H, s). MS (ES+) m/e 218 [MH]+, 220 [MR]+.

10344-42-0, The synthetic route of 10344-42-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Merck Sharp & Dohme Ltd.; US6699859; (2004); B1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem

 

Some tips on 10344-42-0

10344-42-0 4-Bromo-3,6-dichloropyridazine 22030648, apyridazine compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.10344-42-0,4-Bromo-3,6-dichloropyridazine,as a common compound, the synthetic route is as follows.

c) 3,6-Dichloro-4-(3,6-dihydro-2H-pyridin-1-yl)pyridazine 1,2,3,6-Tetrahydropyridine, (1.04 ml) was added to a stirred solution/suspension of 4-bromo-3,6-dichloropyridazine (2.0 g, 8.8 mmol) and potassium carbonate (2.4 g) in dry DMF (10 ml) at room temperature under nitrogen. The mixture was stirred at room temperature for 5 hours. The reaction was poured into water (100 ml) and extracted with ethyl acetate (*3). The combined extracts were washed with water (200 ml), brine, dried (MgSO4), filtered and evaporated. The residue was triturated with ether/petroleum ether to afford a white powder (1.96 g, 97%). 1H NMR (250 MHz, CDCl3) 6.82 (1H, s), 5.97 (1H, m), 5.80 (1H, m), 3.77 (2H, m), 3.59 (2H, m), 2.38 (2H, m). MS (ES+) 232 [MH]+.

10344-42-0 4-Bromo-3,6-dichloropyridazine 22030648, apyridazine compound, is more and more widely used in various.

Reference£º
Patent; Merck Sharp & Dohme Ltd.; US6319924; (2001); B1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem