Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In a patent, category: pyridazine, molecular formula is C4H2Cl2N2, introducing its new discovery. category: pyridazine
The present disclosure relates to bifunctional compounds, which find utility as modulators of tau protein. In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a VHL or cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds tau protein, such that tau protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of tau. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of tau protein. Diseases or disorders that result from aggregation or accumulation of tau protein are treated or prevented with compounds and compositions of the present disclosure.
I am very proud of our efforts over the past few months and hope to 141-30-0 help many people in the next few years.category: pyridazine
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1266 – PubChem