Tag: M.W:200-300

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. HPLC of Formula: C5H5IN2O, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 17321-35-6, name is 3-Iodo-6-methoxypyridazine. In an article£¬Which mentioned a new discovery about 17321-35-6

First synthesis of novel 3,3?-bipyridazine derivatives as new potent antihepatocellular carcinoma agents

Hepatocellular carcinoma is one of the most common kind of cancers in clinical, and its clinical treatment is quite difficult. The latest research suggests that pyridazinone with a novel molecular skeleton shows excellent activity against hepatocellular carcinoma in vitro and in vivo. Considering YHHU-759 as the leading compound for reasonable structure modification, a series of 3,3?-bipyridazine derivatives including 8 novel compounds in this study were designed, synthesized and screened for their anti-hepatoma activities against liver cancer cell lines SMMC-7721, BEL-7402 and QGY-7703 in vitro. The result shows that all of the 3,3?-bipyridazine derivatives have good anti-hepatoma activities.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 17321-35-6, help many people in the next few years.HPLC of Formula: C5H5IN2O

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Pyridazine | C4H4N3031 – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. Product Details of 91063-19-3, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 91063-19-3

(HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS

The present invention relates to (hetero)aryl compounds of general formula (I) wherein the groups and radicals A, B, Q, W, X, Y, Z, R1, R2, R4a, R4b, R5a, R5b, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to 10 the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.

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Pyridazine | C4H4N2918 – PubChem

 

Application of 10344-42-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, molecular formula is C4HBrCl2N2. In a Patent£¬once mentioned of 10344-42-0

HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON’S DISEASE

The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease. Formula (I). In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 10344-42-0, and how the biochemistry of the body works.Application of 10344-42-0

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Pyridazine | C4H4N3012 – PubChem

 

Related Products of 41933-33-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 41933-33-9, Name is 2-Benzyl-4,5-dichloropyridazin-3(2H)-one,introducing its new discovery.

SERINE/THREONINE KINASE INHIBITORS

Compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such diseases, or associated pathological conditions are disclosed.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 41933-33-9, and how the biochemistry of the body works.Related Products of 41933-33-9

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Pyridazine | C4H4N3190 – PubChem

 

Related Products of 135034-10-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.135034-10-5, Name is 3-Chloro-6-iodopyridazine, molecular formula is C4H2ClIN2. In a Patent£¬once mentioned of 135034-10-5

ARYL SULFONAMIDE AND SULFONYL COMPOUNDS AS MODULATORS OF PPAR AND METHODS OF TREATING METABOLIC DISORDERS

Aryl sulfonamide and sulfonyl compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 135034-10-5, and how the biochemistry of the body works.Related Products of 135034-10-5

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Pyridazine | C4H4N3061 – PubChem

 

Electric Literature of 492431-11-5, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 492431-11-5, 1-Boc-4-(6-Chloropyridazin-3-yl)piperazine, introducing its new discovery.

Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3

We describe the structural optimization of a lead compound 1 that exhibits dual inhibitory activities against FLT3 and CDK4. A series of pyrido[4?,3?:4,5]pyrrolo[2,3-d]pyrimidine derivatives was synthesized, and SAR analysis, using cell-based assays, led to the discovery of 28 (AMG 925), a potent and orally bioavailable dual inhibitor of CDK4 and FLT3, including many FLT3 mutants reported to date. Compound 28 inhibits the proliferation of a panel of human tumor cell lines including Colo205 (Rb +) and U937 (FLT3WT) and induced cell death in MOLM13 (FLT3ITD) and even in MOLM13 (FLT3ITD, D835Y), which exhibits resistance to a number of FLT3 inhibitors currently under clinical development. At well-tolerated doses, compound 28 leads to significant growth inhibition of MOLM13 xenografts in nude mice, and the activity correlates with inhibition of STAT5 and Rb phosphorylation.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 492431-11-5. In my other articles, you can also check out more blogs about 492431-11-5

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Pyridazine | C4H4N3239 – PubChem

 

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. SDS of cas: 135034-10-5, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 135034-10-5, name is 3-Chloro-6-iodopyridazine. In an article£¬Which mentioned a new discovery about 135034-10-5

POLYMORPHIC AND HYDRATE FORMS, SALTS AND PROCESS FOR PREPARING 6-{DIFLUORO[6-(1-METHYL-1H-PYRAZOL-4-YL)[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-3-YL]METHYL}QUINOLINE

The invention relates to novel polymorphic and hydrate forms and salts of 6-{difluoro[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline, to methods for their preparation, to pharmaceutical compositions comprising at least one of said polymorphic or hydrate forms or salts, and to the therapeutic and/or prophylactic use of such compositions. The invention also provides new manners for preparing said compound.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 135034-10-5, help many people in the next few years.SDS of cas: 135034-10-5

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3047 – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 20074-67-3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 20074-67-3, Name is Perchloropyridazine, molecular formula is C4Cl4N2

6-PYRIDONE-2-CARBAMOYL-AZOLES AND THEIR USE AS HERBICIDES

6-Pyridone-2-carbamoylazoles of the general formula (I) are described as herbicides. In this formula (I), W, X and Z represent radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen. Q represents a 5-membered radical such as oxadiazyl.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 20074-67-3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 20074-67-3, in my other articles.

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Pyridazine | C4H4N2905 – PubChem

 

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Quality Control of 3-Chloro-6-iodopyridazine. Introducing a new discovery about 135034-10-5, Name is 3-Chloro-6-iodopyridazine

PESTICIDALLY ACTIVE TETRACYCLIC HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS

Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Quality Control of 3-Chloro-6-iodopyridazine, you can also check out more blogs about135034-10-5

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Pyridazine | C4H4N3043 – PubChem

 

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of 6-Iodopyridazin-3-amine. Introducing a new discovery about 187973-60-0, Name is 6-Iodopyridazin-3-amine

Imidazo[1,2-b]pyridazines. XXI syntheses of some 3-acylaminomethyl-6-(chloro and iodo)-2-(substituted phenyl)-imidazo[1,2-b]pyridazines and -imidazo[1,2-a]pyridines and their interaction with central and mitochondrial benzodiazepine receptors

A series of 3-acylaminomethyl-6-(chloro, iodo and methyl)-2-(phenyl, 4?-t-butylphenyl, 4?-cyclohexyl-phenyl, biphenyl-4?-yl, 4?-chlorophenyl and 4?-iodophenyl)imidazo[1,2-b]pyridazines and imidazo[1,2-a]pyridines has been prepared and examined for interaction with central and mitochondrial (peripheral-type) benzodiazepine receptors. The imidazo[1,2-b]pyridazines were generally more selective for the mitochondrial receptors than the corresponding imidazo[1,2-a]pyridines. Of these compounds, 3-acetamidomethyl-2-(biphenyl-4?-yl)-6-chloroimidazo[1,2-b]pyridazine (9) proved to be the most selective in studies of the displacement of [3H]diazepam from peripheral-type and central benzodiazepine receptors (IC50 2-8 nM and 0% displacement at 1000 nM, respectively).

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 6-Iodopyridazin-3-amine, you can also check out more blogs about187973-60-0

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2940 – PubChem