Tag: M.W:200-300

187973-60-0, Name is 6-Iodopyridazin-3-amine, belongs to pyridazine compound, is a common compound. Product Details of 187973-60-0In an article, once mentioned the new application about 187973-60-0.

The present invention relates to compounds of formula (I) and its use for the treatment of neurological disorders.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2930 – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Quality Control of 5-Iodo-2,3-dihydropyridazin-3-one, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 825633-94-1

The present invention provides a compound of general Formula (I) having histone deacetylase (HDAC) and/or Cyclin-dependent kinase (CDK) inhibitory activity, a pharmaceutical composition comprising the compound, and a method useful to treat diseases using the compound

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2980 – PubChem

Related Products of 1178884-53-1, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 1178884-53-1, Name is 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one,introducing its new discovery.

no abstract published

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2998 – PubChem

1698-53-9, Name is 4,5-Dichloro-2-phenylpyridazin-3(2H)-one, belongs to pyridazine compound, is a common compound. HPLC of Formula: C10H6Cl2N2OIn an article, once mentioned the new application about 1698-53-9.

Substituted 5-hydrazinopyridazin-3(2H)-ones, e.g., 4-chloro-2-(3-trifluoromethylphenyl)-5-(1-methylhydrazino)-pyridazin-3(2H)-one or 4-chloro-2-(2-fluoro-5-trifluoromethylphenyl)-5-(1-methylhydrazino)-pyridazin-3(2H)-one, are prepared by treating halogenated pyridazin-3-(2H)-ones with hydrazine and substituted hydrazines and are useful as central nervous system depressants and sleep inducers.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3085 – PubChem

Application of 5788-58-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 5788-58-9, Name is 4,5-Dibromopyridazin-3(2H)-one,introducing its new discovery.

This report describes replacement of the 4-(4-fluorophenyl)piperidine moiety in our CCR2 antagonists with 4-heteroaryl piperidine and 4-(carboxyphenyl)-piperidine subunits. Some of the resulting analogs retained potency in our CCR2 binding assay and had improved selectivity versus the IKr channel; poor selectivity against IKr had been a liability of earlier analogs in this series.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3179 – PubChem

Synthetic Route of 1698-53-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1698-53-9, Name is 4,5-Dichloro-2-phenylpyridazin-3(2H)-one, molecular formula is C10H6Cl2N2O. In a Article，once mentioned of 1698-53-9

The intramolecular distances dC-Cl for chlorine bound to sp2 carbon and to sp3 carbon, respectively, and the 35Cl NQR frequencies assigned to the corresponding Cl atoms correlate quite well according to the theory: nu(35Cl) ca. (dC-Cl)-3.The relation is nu(35Cl) = (4 +/- 6) MHz + (166 +/- 31)*1E6*(dC-Cl)-3* MHz*pm3 for -Cl and nu(35Cl) = (21 +/- 5) MHz + (101 +/- 25) *1E6 * (dC-Cl)-3 *MHz * pm3 for -Cl.The crystal structures and chemical bonds of (1) (4-methyl-4-trichloromethyl-2,5-cyclohexadiene-1-one), (2) (2-chloro-4,5-dimethyl-4-trichloromethyl-2,5-cyclohexadiene-1-one), (3) (4,5-dichloro-1- phenyl-pyridazine-6-one), and (4) ( 2,2,4,5-tetrachloro-cyclopentene-1,3-dione) were studied by single crystal X-ray diffraction and 35Cl nuclear quadrupole resonance (NQR). (1) crystallizes with the space group D152h-Pbca, Z = 8.The lattice constants are a= 1206.0(3) pm, b= 1341.3(3) pm, and c = 1178.8(3) pm. (2) crystallizes monoclinic, space group C52h-P21/c, Z = 4, a = 696.3(3) pm, b = 1404.0(5) pm, c = 1151.4(5) pm, and beta = 100.23(1) deg. (3) crystallizes in the orthorhombic space group D42-P212121 , Z = 4, a = 4303(1) pm, b = 586.8(2) pm, and c = 390.5(1) pm. (4) crystallizes cubic, space group T4h-Fd3, with 48 molecules in the unit cell, a = 2181.5(5) pm.The 35Cl NQR spectra were observed for the two 2,5-cyclohexadiene-1-ones, (1) and (2) in the temperature range 77 less equal T/K less melting point.For (3), the 35Cl NQR spectra was determined at T = 77 K and T = 295 K.No phase transition has been found for the three compounds in the temperature range in which the 35Cl NQR spectroscopy was performed.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1698-53-9

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3090 – PubChem

Reference of 1698-53-9, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1698-53-9, Name is 4,5-Dichloro-2-phenylpyridazin-3(2H)-one, molecular formula is C10H6Cl2N2O. In a Patent，once mentioned of 1698-53-9

4-Chloro-5-amino-2-phenyl-3(2H)-pyridazinone is prepared from 4,5-dichloro-2-phenyl-3(2H)-pyridazinone and ammonia in high yield and substantially free from 4-amino-5-chloro-2-phenyl-3(2 H)-pyridazinone in a method comprising reacting 4,5-dichloro-2-phenyl-3(2H)-pyridazinone with aqueous ammonia in the presence of a catalyst which is capable of selectively exchanging the 5-chlorine atom in 4,5-dichloro-2-phenyl-3(2H)-pyridazinone with a leaving group of such a nature that the resulting intermediate compound is capable of alkylating ammonia to 4-chloro-5-amino-2-phenyl-3(2H)-pyridazinone in high yield in the reaction medium, thereby regenerating the catalyst. The end product is isolated by filtration after the reaction and washed with water, and the mother liquor plus the wash water are used as reaction medium for the next batch.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 1698-53-9. In my other articles, you can also check out more blogs about 1698-53-9

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3077 – PubChem

Related Products of 1698-53-9, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 1698-53-9, molcular formula is C10H6Cl2N2O, introducing its new discovery.

The 13C NMR spectra of a series of 2-X-4-Y-5-Z-substituted 2-H-pyridiazin-3-ones were measured and assigned on the basis of results from one-dimensional semiselective INEPT ore one-dimensional relayed coherence transfer (HICUUP) experiments.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1698-53-9 is helpful to your research. Related Products of 1698-53-9

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N3103 – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: pyridazine. Introducing a new discovery about 5788-58-9, Name is 4,5-Dibromopyridazin-3(2H)-one

2-Cyanopyridazin-3(2H)-ones are novel, effective, selective and electrophilic cyanating agents. A variety of amino, thiol and carbon nucleophiles are chemoselectively N-, S- or C-cyanated in excellent yield using 2-cyanopyridanzin-3(2H)-ones in water or tetrahydrofuran.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: pyridazine, you can also check out more blogs about5788-58-9

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3174 – PubChem

Synthetic Route of 1178884-53-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1178884-53-1, Name is 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one, molecular formula is C5H4BrClN2O. In a Patent，once mentioned of 1178884-53-1

Pyridazinone compounds of Formula (I) including stereoisomers, tautomers, and pharmaceutically acceptable salts there of, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula (I) for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2999 – PubChem