Tag: M.W:200-300

Recommanded Product: 135034-10-5, While the job of a research scientist varies, most chemistry careers in research are based in laboratories, where research is conducted by teams following scientific methods and standards. 135034-10-5, Name is 3-Chloro-6-iodopyridazine, molecular formula is C4H2ClIN2. In a Article，once mentioned of 135034-10-5

Copper is king! A convenient method for the synthesis of trifluoromethylated heteroaromatic compounds under mild conditions has been developed based on the observation that 1 can be reduced by certain metals (see scheme). Substrate 1 is assumed to be reduced by copper via a single-electron transfer mechanism, and CuCF3 is the most probable intermediate in this reaction. DMF=N,N-dimethylformamide, Tf=triflate.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N3073 – PubChem

Computed Properties of C4HBrCl2N2, As a society publisher, everything we do is to support the scientific community – so you can trust us to always act in your best interests, and get your work the international recognition that it deserves. 10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine, molecular formula is C4HBrCl2N2. In a Patent，once mentioned of 10344-42-0

1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-alkoxy moiety at the 6-position, are selective ligands for GABA Areceptors, in particular having high affinity for the alpha2 and/or alpha3 subunit thereof, are useful in the treatment of anxiety and convulsions.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3017 – PubChem

Formula: C10H6Cl2N2O, The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research.

Commercially available anilines were converted by a two step, one-pot process to the corresponding pyridazinones in good to excellent yields. During the process research, a significant halogen exchange was confirmed and prevented which allowed the process to be scaled to multikilogram quantities.

The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 1698-53-9Formula: C10H6Cl2N2O

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3117 – PubChem

Application of 181355-92-0, The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic and theoretical assessments of solvent structures and their interactions with reaction intermediates and transition states.

Compoundshaving the chemical structure of formula (I) are disclosed; as well as process for theirpreparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Application of 181355-92-0, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 181355-92-0, in my other articles.

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N3224 – PubChem

Modeling chemical reactions helps engineers virtually understand the chemistry, optimal size and design of the system, and how it interacts with other physics that may come into play. Reference of 187973-60-0

The present invention relates to radiolabeled compounds of formula (I) wherein either A, B, R1, R2, is labeled with a radionuclide selected from 3H, 11C and 18F and its use for imaging alpha synuclein and/or Abeta deposits in mammals.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 187973-60-0. In my other articles, you can also check out more blogs about 187973-60-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2923 – PubChem

Electric Literature of 1698-53-9, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1698-53-9, Name is 4,5-Dichloro-2-phenylpyridazin-3(2H)-one, molecular formula is C10H6Cl2N2O. In a Article，once mentioned of 1698-53-9

Divergent C-H functionalization reactions (arylation, carboxylation, olefination, thiolation, acetoxylation, halogenation, naphthylation) using a pyridazinone moiety as an internal directing group were successfully established. This approach offers a late-stage, ortho-selective diversification of a biologically active pyridazinone scaffold. Seven series of novel pyridazinone analogues were synthesized conveniently as the synthetic precursors of potential sortase A (SrtA) inhibitors.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N3102 – PubChem

286946-24-5, Name is Methyl 3,6-dichloropyridazine-4-carboxylate, belongs to pyridazine compound, is a common compound. SDS of cas: 286946-24-5In an article, once mentioned the new application about 286946-24-5.

Compounds of formula I, wherein R1, R2, R3, X1, X2 and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2900 – PubChem

With the volume and accessibility of scientific research increasing across the world, it has never been more important to continue building the reputation for quality and ethical publishing we’ve spent the past two centuries establishing. Application of 41933-33-9

Disclosed herein are antibacterial and antimicrobial compositions and methods of use. Also disclosed are screening assays for identification of an agent that specifically inhibits DsbB or bVKOR. Such methods are useful, for example, in identifying antibacterial and antimicrobial agents and compositions.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 41933-33-9 is helpful to your research. Application of 41933-33-9

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N3189 – PubChem

1178884-53-1, Name is 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one, belongs to pyridazine compound, is a common compound. Safety of 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-oneIn an article, once mentioned the new application about 1178884-53-1.

This application discloses 5-phenyl-1H-pyridin-2-one, 6-phenyl-2H-pyridazin-3-one, and 5-Phenyl-1H-pyrazin-2-one derivatives according to generic Formulae I-III: wherein, variables Q, R, X, X’, Y1, Y2, Y2′, Y3, Y4, Y5, m, and n are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formulae I-III and at least one carrier, diluent or excipient

The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 1178884-53-1Safety of 4-Bromo-6-chloro-2-methylpyridazin-3(2H)-one

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2993 – PubChem

Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation. Application of 135034-10-5

The present invention provides compounds of formula (I): their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms.In my other articles, you can also check out more blogs about 135034-10-5Application of 135034-10-5, you can also check out more blogs aboutApplication of 135034-10-5

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N3038 – PubChem