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This invention relates to (isopropyl and tertiary butyl-amino-2-hydroxypropoxy)phenyl-3[2H]-pyridazinones which have beta-adrenoceptor antagonist activity.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2270 – PubChem

 

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The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2004 – PubChem

 

The important role of 3-Chloro-6-methylpyridazine

In conclusion, we affirm that quantitative kinetic descriptions of catalytic behavior continue to navigate research efforts intended to model and predict the effects of solvation within porous materials. Read on for other articles about 1121-79-5.name: 3-Chloro-6-methylpyridazine

name: 3-Chloro-6-methylpyridazine, Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. 1121-79-5, Name is 3-Chloro-6-methylpyridazine, molecular formula is C5H5ClN2. In a article,once mentioned of 1121-79-5

We have developed an improved synthesis of 3-(hetero)aryl pyrazolo[1,5-a]pyridines (such as 3-(2,5-dichloropyrimidin-4-yl)pyrazolo[1,5-a] pyridine (8)) via an optimized synthesis and Suzuki coupling of 3-pyrazolo[1,5-a]pyridine boronic ester 10. These conditions are applicable to both high throughput chemistry and large scale synthesis of these medicinally important compounds. The scope of this chemistry has been further extended to include the synthesis and coupling of a novel boronic ester, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7-dihydro-5H-pyrazolo[5,1-b] [1,3]oxazine (43).

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N652 – PubChem

 

Simple exploration of 3,6-Dichloropyridazine

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Preparation of a series of new aryl diazinyl ketoximes (7a,b – 12a,b) required as synthetic building blocks is described. Separation of the E/Z-isomers obtained was achieved by means of chromatography, their configuration was assigned using nmr techniques. Moreover, procedures for the synthesis of the starting ketones (1b – 6b) are given.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N1726 – PubChem

 

Brief introduction of 6-Chloropyridazine-3-carbonitrile

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35857-89-7, Name is 6-Chloropyridazine-3-carbonitrile, belongs to pyridazine compound, is a common compound. Application In Synthesis of 6-Chloropyridazine-3-carbonitrileIn an article, once mentioned the new application about 35857-89-7.

A highly efficient and practical Ru-catalyzed direct C-H functionalization of indolines and N-alkylaniline with a simple pivaloyl as a directing group is developed. Broad substrate scopes with respect to N-heteroarenes and olefins are observed. The selective C7-position alkynylation for indoline also proceeds well by using inexpensive ruthenium as a catalyst, and pivaloyl as a directing group.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N996 – PubChem

 

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Compounds of formula (I) Z-Ar1?Ar2??(I) wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylenedioxy)phenyl; carbazolyl; tetrahydrocarbazolyl; naphthyl; and phenyl; wherein the phenyl is substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by alpha7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N1215 – PubChem

 

Properties and Exciting Facts About 34231-77-1

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Application of 34231-77-1, The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research.

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as herbicides.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N779 – PubChem

 

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The potential utility of polymethylhydrosiloxane (PMHS) as a reducing agent for reductive N-alkylation of aromatic amines and nitro compounds using nitriles as an alkylating agent and Pd(OH)2/C as a catalyst is described. The application of this method for the synthesis of several heterocyclic compounds is also reported.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N966 – PubChem

 

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The invention relates to antibacterial compounds of formula I wherein R1a, R2a, R2b, R3a, R3b, R4, R5, U1, U2, U3, U4, V1, V2, V3, V4, X and Q and n are as defined in the specification. It further relates pharmaceutical compositions containing these compounds and the uses of these compounds in the manufacture of medicaments for the treatment of bacterial infections. These compounds are useful antimicrobial agents effective against a variety of human and veterinary pathogens including among others Gram-positive and Gram-negative aerobic and anaerobic bacteria.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N1158 – PubChem

 

You Should Know Something about 3,6-Dichloropyridazine

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. A catalyst does not appear in the overall stoichiometry of the reaction it catalyzes. “Application of 141-30-0

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This report describes replacement of the 4-(4-fluorophenyl)piperidine moiety in our CCR2 antagonists with 4-heteroaryl piperidine and 4-(carboxyphenyl)-piperidine subunits. Some of the resulting analogs retained potency in our CCR2 binding assay and had improved selectivity versus the IKr channel; poor selectivity against IKr had been a liability of earlier analogs in this series.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N1854 – PubChem