Tag: M.W:100-200

Related Products of 28682-70-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 28682-70-4, Pyridazine-4,5-diamine, introducing its new discovery.

4-Nitro-3-R1-6-R2-pyridazines (1) (a, R1 = R2 =2-pyridyl; b, R1 = H, R2 = phenyl; c, R1 = H, R2 = p-methoxyphenyl; d, R1 = R2 = H) are aminated by liquid ammonia/potassium permanganate to the corresponding 5-amino-4-nitropyridazines 3a-d.The 4-cyano-3-R1-6-R2-pyridazines 4a,b are only aminated in the presence of potassium amide in liquid ammonia/potassium permanganate to give the 5-amino-4-cyanopyridazines 6a,b.The 5-amino-4-nitropyridazines 3a,b,d are converted to the 4,5-diaminopyridazines 7a,b,d by reduction over a Pd/C catalyst.Reaction of7b with glyoxal leads to 5-phenylpyrazino<2,3-d>pyridazine (8b).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 28682-70-4. In my other articles, you can also check out more blogs about 28682-70-4

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N359 – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 141-30-0. Introducing a new discovery about 141-30-0, Name is 3,6-Dichloropyridazine

The preparations and spectral data for nine new N,N’-chelating ligands (5)-(13), each consisting of a pyrazole group N-linked to an azine or azole, are described.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1904 – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 19064-67-6, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 19064-67-6, Name is 6-Chloro-3-hydroxypyridazine, molecular formula is C4H3ClN2O

The present invention is directed to substituted pyridinone compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington’s disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N735 – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. SDS of cas: 141-30-0. Introducing a new discovery about 141-30-0, Name is 3,6-Dichloropyridazine

A novel strategy for efficient synthesis of various substituted heterocycles as kinase-directed combinatorial libraries is described. The general scheme involves capture of various dichloroheterocycles onto solid support and further elaborations by aromatic substitution with amines at elevated temperature or by anilines, boronic acids, and phenols via palladium-catalyzed cross-coupling reactions, thus the scaffold itself is transformed into a diversity element within the combinatorial scheme. Libraries consisting of discrete and highly diverse heterocyclic small molecules constructed with these chemistries are currently being evaluated in a variety of cell and protein-based assays. Copyright

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.SDS of cas: 141-30-0, you can also check out more blogs about141-30-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1675 – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 141-30-0, name is 3,6-Dichloropyridazine, introducing its new discovery. Recommanded Product: 141-30-0

A series of azines featuring differently halogen and protic group substituted pyridine, pyrimidine and pyridazine compounds have been synthesized and studied in terms of their crystal structures in order to develop a better understanding of the links between structural conditions and molecular packing behavior. Complemented by the structure results of related compounds known from the literature, intermolecular contact relationships connected to the present substance types were found, having potential use in future crystal engineering of similar compounds. This primarily involves the formation of N?I contacts aside from specific halogen?halogen and hydrogen bond type interactions.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1744 – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Safety of 6-Chloropyridazine-3-carboxylic acid, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 5096-73-1, Name is 6-Chloropyridazine-3-carboxylic acid, molecular formula is C5H3ClN2O2

The direct and selective synthesis of phenols from aryl/heteroaryl halides and KOH has been achieved through the use of highly active monophosphine-based catalysts derived from Pd2dba3 and ligands L1 or L2 and the biphasic solvent system 1,4-dioxane/H2O. We have also demonstrated a one-pot method of phenol formation/alkylation for the preparation of alkyl aryl ethers from aryl halides. In many instances, this protocol overcomes limitations in existing Pd-catalyzed coupling reactions of aliphatic alcohols with aryl halides. Finally, we demonstrate that substituted benzofurans can be prepared efficiently via a Pd-catalyzed phenol formation/cyclization protocol starting from 2-chloroaryl alkynes. Copyright

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Safety of 6-Chloropyridazine-3-carboxylic acid, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5096-73-1, in my other articles.

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2043 – PubChem

Reference of 20375-65-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.20375-65-9, Name is 3-Phenyl-6-chloropyridazine, molecular formula is C10H7ClN2. In a article，once mentioned of 20375-65-9

N-But-3-enyl-alpha- and beta-amino acids can be prepared by cleaving 1,3-oxazolidin-5-ones and 1,3-oxazinan-6-ones in the presence of allylsilanes and boron trifluoride etherate at room temperature in good to excellent yields. Georg Thieme Verlag Stuttgart.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2762 – PubChem

Electric Literature of 1837-55-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 1837-55-4, 3,5-Dichloropyridazine, introducing its new discovery.

In the present studies, the synthesis of new energetic materials based on the pyridazine scaffold and their characterization is the main subject. For this purpose, desired 3,5-dimethoxy-4,6-dinitropyridazine-1-oxide (7) was synthesized in the first instance. The persubstituted pyridazine precursor laid the groundwork for further preparative modification. The targeted functionalization through the regioselective introduction of various smaller amine nucleophiles such as methylamine or 2-aminoethanol gave several new energetic materials. Among them are 3,5-bis(methylamino)-4,6-dinitropyridazine-1-oxide (8), 3,5-bis(methylnitramino)-4,6-dinitropyridazine-1-oxide (9), 3,5-bis(dimethylamino)-4,6-dinitropyridazine-1-oxide (10), and 3,5-bis((2-hydroxyethyl)amino)-4,6-dinitropyridazine-1-oxide (11). With the aim of increasing the detonation performance, compound 8 was additionally nitrated and 3,5-bis(methylnitramino)-4,6-dinitropyridazine-1-oxide (9) was obtained. These new energetic materials were characterized and identified by multinuclear NMR (1H, 13C, 14N, 15N) and IR spectroscopy, elemental analysis and mass spectrometry. In addition, their sensitivities toward impact, friction and electrostatic discharge were thoroughly examined. Furthermore, obtained single-crystals of the substances were characterized by low-temperature single-crystal X-ray diffraction.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 1837-55-4. In my other articles, you can also check out more blogs about 1837-55-4

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1194 – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C5H4N2O2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 2164-61-6, Name is Pyridazine-3-carboxylic acid, molecular formula is C5H4N2O2

Rate constants for the reaction of six possible diazine monocarboxylates with diazodiphenylmethane (DDM) in ethanol, and also for the hydrolysis of the corresponding methyl carboxylate esters, have been determined at four selected temperatures.Correlations with sums of the Hammett ? constants for ring nitrogens treated as substituents, which are fairly satisfactory for the reaction with DDM at 30 deg C (rhoDDM = 0.64, log k0 = -1.54, r = 0.92, s = 0.12) and for ester hydrolysis (rhoEH = 2.28, log k0 = -3.36, r = 0.94, s = 0.36) are, however, excellent for the intercorrelation of the two reaction series (rhoDDM/rhoEH = 0.34, r = 0.99, s = 0.12).The reactivity of ortho- and para-diazine dicarboxylates in the reaction with DDM, in ethanol and dimethylformamide, has been investigated and compared with the corresponding reactions of ortho- and para-benzene- and pyridine-dicarboxylates.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N492 – PubChem

Application of 141-30-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.141-30-0, Name is 3,6-Dichloropyridazine, molecular formula is C4H2Cl2N2. In a article，once mentioned of 141-30-0

Organometallic complexes of practically unsubstituted (non-chelating) azines and their benzannulated derivatives, possible N-heterocyclic carbenes containing at least one double bond, and boron-, boron?nitrogen, silicon-, tri- and hexaphosphorus analogs of azines are considered in the view of their synthetic availability, coordination modes, and possible application in catalysis and materials chemistry.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 141-30-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1883 – PubChem