Tag: 96.0874

La Manna, Gianfranco et al. published their research in Gazzetta Chimica Italiana in 1972 | CAS: 20733-10-2

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. Pyridazine and phthalazine have quite different spectroscopic properties compared with their isomers, pyrazine and quinoxaline. The activity depends upon the changes of substituted groups in the pyridazine ring system resulting in different biological activities. In addition, the natural pyrimidine bases uracil, thymine, and cytosine, which are constituents of the nucleic acids, are found to be the most important naturally occurring diazines.COA of Formula: C4H4N2O

Electronic structure of groups of isomeric heteroaromatic systems. V. Monohydroxydiazines and diazinones was written by La Manna, Gianfranco;Cignitti, Maurizio. And the article was included in Gazzetta Chimica Italiana in 1972.COA of Formula: C4H4N2O This article mentions the following:

π-Electron energies and π-dipole moments were calculated for 3-pyridazinol (I), 3(2H)-pyridazinone (II), 2-pyrimidinol (III), 2(1H)-pyrimidinone (IV), and 9 other pyridazine and pyrimidine keto-enol tautomers. The lactam structures were the most stable. In the experiment, the researchers used many compounds, for example, 4-Hydroxypyridazine (cas: 20733-10-2COA of Formula: C4H4N2O).

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. Pyridazine and phthalazine have quite different spectroscopic properties compared with their isomers, pyrazine and quinoxaline. The activity depends upon the changes of substituted groups in the pyridazine ring system resulting in different biological activities. In addition, the natural pyrimidine bases uracil, thymine, and cytosine, which are constituents of the nucleic acids, are found to be the most important naturally occurring diazines.COA of Formula: C4H4N2O

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem

 

Barlin, Gordon B. et al. published their research in Australian Journal of Chemistry in 1979 | CAS: 20733-10-2

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. The pyridazine derivatives are mostly present in biologically active compounds and are also present with different pharmacophores. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Quality Control of 4-Hydroxypyridazine

Proton NMR studies of protonation in pyridazin-3(2H)-one and 6-hydroxypyridazin-3(2H)-one was written by Barlin, Gordon B.;Fenn, M. David. And the article was included in Australian Journal of Chemistry in 1979.Quality Control of 4-Hydroxypyridazine This article mentions the following:

A 1H NMR study of protonation in pyridazin-3-ol and pyridazine-3,6-diol revealed that the processes are not simple and suggests that a mobile tautomeric equilibrium may be involved. In the experiment, the researchers used many compounds, for example, 4-Hydroxypyridazine (cas: 20733-10-2Quality Control of 4-Hydroxypyridazine).

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. The pyridazine derivatives are mostly present in biologically active compounds and are also present with different pharmacophores. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Quality Control of 4-Hydroxypyridazine

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem

 

Albert, Adrien et al. published their research in Journal of the Chemical Society in 1956 | CAS: 20733-10-2

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. Pyridazine and phthalazine have quite different spectroscopic properties compared with their isomers, pyrazine and quinoxaline. Specifically, the pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, cardiotonic, vasodilator, antiarrhythmic, and hypocholesterolaemic.HPLC of Formula: 20733-10-2

Ionization constants of heterocyclic substances. II. Hydroxy-derivatives of nitrogenous six-membered ring-compounds was written by Albert, Adrien;Phillips, J. N.. And the article was included in Journal of the Chemical Society in 1956.HPLC of Formula: 20733-10-2 This article mentions the following:

Acidic and basic ionization constants were determined potentiometrically and in some cases spectrometrically for 87 hydroxy (and related) derivatives of pyridine, quinoline, isoquinoline, acridine, phenanthridine, pyridazine, pyrimidine, pyrazine, cinnoline, phthalazine, quinazoline, quinoxaline, phenazine, triazine, 1,4,5-triazanaphthalene, and 1,4,6-triazanaphthalene. The tautomeric equilibrium between enol and amide in 伪 and 纬-hydroxy derivatives greatly favor the amide form. The preparation of 2-methoxypyrazine, b29 60-1掳, and 3-hydroxypyridine methochloride were described. A m.p. of 57掳 was reported for 2-methyl-1-isoquinolone. In the experiment, the researchers used many compounds, for example, 4-Hydroxypyridazine (cas: 20733-10-2HPLC of Formula: 20733-10-2).

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. Pyridazine and phthalazine have quite different spectroscopic properties compared with their isomers, pyrazine and quinoxaline. Specifically, the pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, cardiotonic, vasodilator, antiarrhythmic, and hypocholesterolaemic.HPLC of Formula: 20733-10-2

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem

 

Albert, Adrien et al. published their research in Journal of the Chemical Society in 1956 | CAS: 20733-10-2

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. Pyridazine and phthalazine have quite different spectroscopic properties compared with their isomers, pyrazine and quinoxaline. Specifically, the pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, cardiotonic, vasodilator, antiarrhythmic, and hypocholesterolaemic.HPLC of Formula: 20733-10-2

Ionization constants of heterocyclic substances. II. Hydroxy-derivatives of nitrogenous six-membered ring-compounds was written by Albert, Adrien;Phillips, J. N.. And the article was included in Journal of the Chemical Society in 1956.HPLC of Formula: 20733-10-2 This article mentions the following:

Acidic and basic ionization constants were determined potentiometrically and in some cases spectrometrically for 87 hydroxy (and related) derivatives of pyridine, quinoline, isoquinoline, acridine, phenanthridine, pyridazine, pyrimidine, pyrazine, cinnoline, phthalazine, quinazoline, quinoxaline, phenazine, triazine, 1,4,5-triazanaphthalene, and 1,4,6-triazanaphthalene. The tautomeric equilibrium between enol and amide in α and γ-hydroxy derivatives greatly favor the amide form. The preparation of 2-methoxypyrazine, b29 60-1°, and 3-hydroxypyridine methochloride were described. A m.p. of 57° was reported for 2-methyl-1-isoquinolone. In the experiment, the researchers used many compounds, for example, 4-Hydroxypyridazine (cas: 20733-10-2HPLC of Formula: 20733-10-2).

4-Hydroxypyridazine (cas: 20733-10-2) belongs to pyridazine derivatives. Pyridazine and phthalazine have quite different spectroscopic properties compared with their isomers, pyrazine and quinoxaline. Specifically, the pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, cardiotonic, vasodilator, antiarrhythmic, and hypocholesterolaemic.HPLC of Formula: 20733-10-2

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem