Synthesis of a novel 6,5-bicyclic hexahydropyridazine derivative was written by Dragovich, Peter S.;Tada, Hiroki;Zhou, Ru. And the article was included in Heterocycles in 1995.Name: (S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid This article mentions the following:
A convergent synthesis of the 6,5-bicyclic hexahydropyridazine derivative I is described in which (3S)-N1-Cbz-piperazic acid Me ester is coupled with the functionalized carboxylic acid fragment II. The Sharpless asym. dihydroxylation reaction (AD) of the 1,1-disubstituted olefin EtOCOC(CH2CH2Me):CH2 is utilized in the preparation of II and is observed to produce the corresponding diol with 44% enantiomeric excess and R stereochem. In the experiment, the researchers used many compounds, for example, (S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid (cas: 65632-62-4Name: (S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid).
(S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid (cas: 65632-62-4) belongs to pyridazine derivatives. Pyridazine-based compounds continued to be a great source of biologically active compounds as evidenced by the number of publications which emerged in 2021. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Name: (S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem