Tag: 232.47

Shimizu, Hiroki et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2011 | CAS: 13526-66-4

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.COA of Formula: C6H3BrClN3

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: Exploration of effective compounds in arthritis models was written by Shimizu, Hiroki;Yamasaki, Tomonori;Yoneda, Yoshiyuki;Muro, Fumihito;Hamada, Tomoaki;Yasukochi, Takanori;Tanaka, Shinji;Toki, Tadashi;Yokoyama, Mika;Morishita, Kaoru;Iimura, Shin. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2011.COA of Formula: C6H3BrClN3 This article mentions the following:

We have discovered imidazo[1,2-b]pyridazine derivatives that show suppressive activity of inflammation in arthritis models. We optimized the substructures of imidazo[1,2-b]pyridazine derivatives to combine potent IKKβ inhibitory activity, TNFα inhibitory activity in vivo and excellent pharmacokinetics. The compound we have acquired, which had both potent activities and good pharmacokinetic profiles based on improved physicochem. properties, demonstrated efficacy on collagen-induced arthritis models in mice and rats. In the experiment, the researchers used many compounds, for example, 3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4COA of Formula: C6H3BrClN3).

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.COA of Formula: C6H3BrClN3

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem

 

Stanovnik, Branko et al. published their research in Synthesis in 1981 | CAS: 13526-66-4

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

3-Bromoimidazo[1,2-b]pyridazine-bromine and 3-bromo-6-chloroimidazo[1,2-b]pyridazine-bromine complexes: new brominating agents for organic compounds was written by Stanovnik, Branko;Tisler, Miha;Drnovsek, Iztok. And the article was included in Synthesis in 1981.Electric Literature of C6H3BrClN3 This article mentions the following:

Title compounds I.HBr.Br2 (R = H or Cl) were prepared and used to brominate a variety of alkenes, ketones, 3-oxoalkanoic esters, and monocyclic and polycyclic N-heterocyclic compounds at room temperature or on gentle heating, monobrominated compounds are obtained in practically quant. yields. In the experiment, the researchers used many compounds, for example, 3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4Electric Literature of C6H3BrClN3).

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem

 

Stanovnik, Branko et al. published their research in Synthesis in 1981 | CAS: 13526-66-4

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

3-Bromoimidazo[1,2-b]pyridazine-bromine and 3-bromo-6-chloroimidazo[1,2-b]pyridazine-bromine complexes: new brominating agents for organic compounds was written by Stanovnik, Branko;Tisler, Miha;Drnovsek, Iztok. And the article was included in Synthesis in 1981.Electric Literature of C6H3BrClN3 This article mentions the following:

Title compounds I.HBr.Br2 (R = H or Cl) were prepared and used to brominate a variety of alkenes, ketones, 3-oxoalkanoic esters, and monocyclic and polycyclic N-heterocyclic compounds at room temperature or on gentle heating, monobrominated compounds are obtained in practically quant. yields. In the experiment, the researchers used many compounds, for example, 3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4Electric Literature of C6H3BrClN3).

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem

 

Stanovnik, Branko et al. published their research in Synthesis in 1981 | CAS: 13526-66-4

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

3-Bromoimidazo[1,2-b]pyridazine-bromine and 3-bromo-6-chloroimidazo[1,2-b]pyridazine-bromine complexes: new brominating agents for organic compounds was written by Stanovnik, Branko;Tisler, Miha;Drnovsek, Iztok. And the article was included in Synthesis in 1981.Electric Literature of C6H3BrClN3 This article mentions the following:

Title compounds I.HBr.Br2 (R = H or Cl) were prepared and used to brominate a variety of alkenes, ketones, 3-oxoalkanoic esters, and monocyclic and polycyclic N-heterocyclic compounds at room temperature or on gentle heating, monobrominated compounds are obtained in practically quant. yields. In the experiment, the researchers used many compounds, for example, 3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4Electric Literature of C6H3BrClN3).

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem

 

Stanovnik, Branko et al. published their research in Synthesis in 1981 | CAS: 13526-66-4

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

3-Bromoimidazo[1,2-b]pyridazine-bromine and 3-bromo-6-chloroimidazo[1,2-b]pyridazine-bromine complexes: new brominating agents for organic compounds was written by Stanovnik, Branko;Tisler, Miha;Drnovsek, Iztok. And the article was included in Synthesis in 1981.Electric Literature of C6H3BrClN3 This article mentions the following:

Title compounds I.HBr.Br2 (R = H or Cl) were prepared and used to brominate a variety of alkenes, ketones, 3-oxoalkanoic esters, and monocyclic and polycyclic N-heterocyclic compounds at room temperature or on gentle heating, monobrominated compounds are obtained in practically quant. yields. In the experiment, the researchers used many compounds, for example, 3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4Electric Literature of C6H3BrClN3).

3-Bromo-6-chloroimidazo[1,2-b]pyridazine (cas: 13526-66-4) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.Electric Literature of C6H3BrClN3

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem