Heterocyclic Building Blocks-Pyridazine

Application of 20375-65-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.20375-65-9, Name is 3-Phenyl-6-chloropyridazine, molecular formula is C10H7ClN2. In a Article£¬once mentioned of 20375-65-9

Amino Acid-Derived Chiral Acyl Nitroso Compounds: Diastereoselectivity in Intermolecular Hetero Diels-Alder Reactions

The diastereoselectivities of chiral acyl nitroso dienophiles derived from optically pure N-protected alpha-amino hydroxamic acids have been determined in intermolecular hetero Diels-Alder reactions.The cycloaddition reactions afforded synthetically useful quantities of functionally rich, optically pure cycloadducts, useful for the preparation of a variety of compounds of potential biological interest.Molybdenum hexacarbonyl reduction of the cycloadducts gave optically pure allylic alcohols.Osmium teraoxide-catalyzed dihydroxylation of several bis-allylically substituted intermediates gave only the diastereomerically pure diols corresponding to naturally occurring 2′,3′-dihydroxynucleoside analogs.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2729 – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 27372-38-9, name is 6-Oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid, introducing its new discovery. COA of Formula: C5H6N2O3

Solid-state and solvent-free synthesis of azines, pyrazoles, and pyridazinones using solid hydrazine

Azines, pyrazoles, and pyridazinones were isolated as the sole products in high yields (>97%) by grinding solid hydrazine (H3N +NHCO2-) with di-carbonyl compounds or by their reaction in the absence of solvent. Neither catalysts nor additives were needed to promote the reactions. The solid-state and solvent-free reactions proceeded under ambient conditions and did not produce any wastes other than water and carbon dioxide. They are operationally easy, environmentally safe, and readily scalable, allowing for highly selective synthesis of compounds containing the hydrazine motif. Copyright

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Pyridazine | C4H4N1017 – PubChem

 

Reference of 1120-95-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1120-95-2, Name is 3-Chloropyridazine, molecular formula is C4H3ClN2. In a Patent£¬once mentioned of 1120-95-2

HETEROCYCLIC COMPOUND

The present invention provides an agent for the prophylaxis or treatment of autoimmune diseases (e.g., psoriasis, rheumatoid arthritis, inflammatory bowel disease, Sjogren’s syndrome, Behcet’s disease, multiple sclerosis, systemic lupus erythematosus etc.) and the like, which has a superior Tyk2 inhibitory action. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.

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Pyridazine | C4H4N400 – PubChem

 

Reference of 141-30-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.141-30-0, Name is 3,6-Dichloropyridazine, molecular formula is C4H2Cl2N2. In a Patent£¬once mentioned of 141-30-0

3(2H)-pyridazinone derivatives, a process and intermediates for preparing them and medicaments containing them and/or other 3(2H)-pyridazinone derivatives

The subject-matter of the invention are 3(2H)-Pyridazinone derivatives of the general formula wherein R stands for an ethyl or propyl group substituted by a terminal halogen atom or hydroxyl group or a terminal group of the formula in which latter R? represents a hydrogen atom or an optionally substituted benzyl group and R? represents a hydrogen atom or an optionally substituted benzo[1,4]dioxan-2-yl-methyl or benzo[1,4]dioxan-2-yl-ethyl group or a group of the formula in which latter n is 2 or 3 and R? stands for an optionally substituted phenoxy or phenylthio group and X stands for a hydrogen or halogen atom or an optionally substituted saturated or unsaturated 5-or 6-membered heterocyclic group.Furthermore the subject-matter of the invention are a process and intermediates for preparing these compounds and medicaments containing them and/or other 3(2H)-pyridazinone derivatives.The compounds according to the invention inhibit the adrenergic alpha? receptors, have a calcium–antagonistic effect and exert blood pressure lowering action.

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Pyridazine | C4H4N1386 – PubChem

 

Reference of 63910-43-0, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 63910-43-0, Name is 4-Chloro-5-methoxypyridazin-3(2H)-one,introducing its new discovery.

Methyl carbonium ion migration during the reaction of 4-chloro-5-methoxyl- 3(2H)-pyridazinone with trifluoroethylation agents

To synthesize 4-chloro-5-methoxy-2-(beta-trifluoroethyl)-3(2H)- pyridazinone (4), the reactions of 4-chloro-5-methoxy-3(2H)-pyridazinone (5) with RCH2CF3 (R = I, TsO, MsO, TfO) in different solvents were studied. It was found that methyl group migration took place during this reaction. An oxonium salt 9 was suggested as the active intermediate for the formation of the byproduct 4-chloro-5-methoxy-2-methyl-3(2H)-pyridazinone (7) and4-chloro-2-methyl-5-(beta-trifluoroethoxy)-3(2)-pyridazinone(8).

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Pyridazine | C4H4N2193 – PubChem

 

Related Products of 932-22-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.932-22-9, Name is 4,5-Dichloro-3(2H)-pyridazinone, molecular formula is C4H2Cl2N2O. In a Patent£¬once mentioned of 932-22-9

HERBICIDAL PYRIDAZINONE DERIVATIVES

Disclosed are compounds of Formula (1), N-oxides, and salts thereof, wherein W1 is O or S, and R1, R2, R3, G and J are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

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Pyridazine | C4H4N2273 – PubChem

 

Related Products of 1121-79-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1121-79-5, Name is 3-Chloro-6-methylpyridazine, molecular formula is C5H5ClN2. In a Article£¬once mentioned of 1121-79-5

Optimization of a series of multi-isoform PI3 kinase inhibitors

Optimization of the cellular and pharmacological activity of a novel series of PI3 kinase inhibitors targeting multiple isoforms is described.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N684 – PubChem

 

Synthetic Route of 5469-70-5, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 5469-70-5, molcular formula is C4H5N3, introducing its new discovery.

PYRIMIDINEDIONE-FUSED HETEROCYCLIC COMPOUNDS AS TRPA1 MODULATORS

The present invention is related to novel pyrimidinedione-fused heterocyclic compounds as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds describcd herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 5469-70-5 is helpful to your research. Synthetic Route of 5469-70-5

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Pyridazine | C4H4N29 – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, category: pyridazine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 5096-73-1, Name is 6-Chloropyridazine-3-carboxylic acid, molecular formula is C5H3ClN2O2

Intramolecular Desulfitative Coupling: Nickel-Catalyzed Transformation of Diaryl Sulfones into Biaryls via Extrusion of SO2

As a new transformation of organosulfur compounds, intramolecular desulfitative coupling of diaryl sulfones to the corresponding biaryls has been developed with the aid of nickel-NHC catalysts. This catalytic elimination of SO2 was also applicable to alkenyl aryl sulfone to furnish the corresponding alkenyl arene.

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Pyridazine | C4H4N2068 – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 3,6-Dichloro-4,5-diethylpyridazine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 107228-53-5, Name is 3,6-Dichloro-4,5-diethylpyridazine, molecular formula is C8H10Cl2N2

Preparation of substituted pyridazines

A novel process is described for preparing substituted pyridazines, where a less substituted pyridazine is reacted with a carboxylic acid in the presence of a silver ion as catalyst, using peroxydisulfate ion. The reaction is run at a temperature from about 40 to 80 C. in an aqueous solvent system and mineral acid. The substituted pyridazines are useful as intermediates to herbicidal and fungicidal compounds.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2879 – PubChem