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A five-and-six-membered heterocyclic compound as represented by general formula I, pharmaceutically acceptable salt, metabolite, metabolic precursors or drug precursors thereof, preparation method, pharmaceutical composition, and use thereof; the five-and-six-membered heterocyclic compound has activity as a Janus kinase (JAK) inhibitor, and can be used to prepare drugs for treating diseases caused by the abnormal activity of kinase, such as cell proliferation diseases like cancer.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N141 – PubChem

 

Final Thoughts on Chemistry for 6-Chloro-4-methylpyridazin-3-amine

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 64068-00-4 is helpful to your research. Related Products of 64068-00-4

Application of 64068-00-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 64068-00-4, molcular formula is C5H6ClN3, introducing its new discovery.

The synthesis of a group of 2-phenylimidazo[1,2-b]pyridazine-3-acetic esters and acids is described. The structures of the new compounds are supported by 1H-NMR spectra. These compounds were tested in vivo for their anti-inflammatory, analgesic and ulcerogenic activity. All new compounds showed remarkable anti-inflammatory action in the carrageenan rat paw oedema (one third of that for indomethacin) but no significant analgesic activity in the acetic acid writhing test together with negligible ulcerogenic action, and were also found to be lacking inhibitory activity on cyclooxygenase in vitro.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N1064 – PubChem

 

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Electric Literature of 90766-97-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.90766-97-5, Name is 5-Bromo-6-phenylpyridazin-3(2H)-one, molecular formula is C10H7BrN2O. In a Article,once mentioned of 90766-97-5

A highly efficient procedure for introducing aryl or heteroaryl rings at position 5 of the 6-phenyl-(2H)-pyridazin-3-one system using a Suzuki cross-coupling reaction has been developed in the search for new platelet aggregation inhibitors.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3124 – PubChem

 

The important role of 3,5-Dichloropyridazine

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 1837-55-4, name is 3,5-Dichloropyridazine, introducing its new discovery. Computed Properties of C4H2Cl2N2

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N1174 – PubChem

 

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Design, syntheses and structure-activity relationships of N-acetylated piperazine privileged structures containing MC4R agonist compounds were described. The most potent derivatives were low nM MC4R selective full agonists. Several compounds from the series had modest pharmacokinetic properties.

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Pyridazine – Wikipedia,
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A procedure for the cyclization of dipeptidoyl benzotriazolides containing proline derivatives promoted by triethylamine under MW activation is introduced. The reaction is general for a variety of dipeptidoyl benzotriazolides and represents a very practical and convenient method for the preparation of Pro- or Hyp-derived 2,5-diketopiperazines (2,5-DKPs) and bis-DKPs with a disulfide linker. This method can be used for the construction of 2,5-DKP compound libraries and for the synthesis of natural products with diketopiperazine cores. This journal is

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Properties and Exciting Facts About 3-Phenyl-6-chloropyridazine

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Computed Properties of C10H7ClN2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 20375-65-9, name is 3-Phenyl-6-chloropyridazine. In an article,Which mentioned a new discovery about 20375-65-9

The present invention provides a novel compound having a superior activity as an ERR-alpha modulator and useful as an agent for the prophylaxis or treatment of ERR-alpha associated diseases. The present invention relates to a compound represented by the formula (1) wherein each symbol is as defined in the specification, or a salt thereof

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2570 – PubChem

 

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Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 64068-00-4. In my other articles, you can also check out more blogs about 64068-00-4

Synthetic Route of 64068-00-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 64068-00-4, 6-Chloro-4-methylpyridazin-3-amine, introducing its new discovery.

This invention, relates to imidazopyridazine substituted piperidine derivatives (I) and their use as orexin antagonists

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Pyridazine – Wikipedia,
Pyridazine | C4H4N1034 – PubChem

 

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Application In Synthesis of Ethyl 4,6-dichloropyridazine-3-carboxylate, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 679406-03-2, Name is Ethyl 4,6-dichloropyridazine-3-carboxylate, molecular formula is C7H6Cl2N2O2

Disclosed is crystalline Form B of 6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl) amino)-N-(methyl-d3)pyridazine-3-carboxamide. Form B is the HCl salt of a neat crystalline form. Characterization data for Form B are disclosed.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2968 – PubChem

 

Properties and Exciting Facts About 3-Iodo-6-isopropoxypyridazine

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Application of 17321-38-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.17321-38-9, Name is 3-Iodo-6-isopropoxypyridazine, molecular formula is C7H9IN2O. In a Patent,once mentioned of 17321-38-9

invention relates to new compounds of the formula I to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3220 – PubChem