Awesome Chemistry Experiments For 4,5-Dichloro-3(2H)-pyridazinone

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PYRIDAZINONES AND METHODS OF USE THEREOF

Disclosed are compounds according to Formula (A), and related tautomers and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating kidney diseases, using the compounds of Formula (A).

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Pyridazine | C4H4N2283 – PubChem

 

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Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Product Details of 932-22-9. Introducing a new discovery about 932-22-9, Name is 4,5-Dichloro-3(2H)-pyridazinone

HERBICIDAL PYRIDAZINONE DERIVATIVES

The present invention provides a compound of Formula (I) or an agronomically acceptable salt thereof, wherein:R2 is selected from the group consisting of (A1), (A2) and (A3) wherein X1 is N or CR7 X2 is N or CR8 X3 is N or CR9 X4 is N or CR6 R1, R3, R4, R5 R6, R7, R8 and R9 are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), and to their use for controlling weeds, in particular in crops of useful plants.

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A novel and practical animation of 4,5-dichloropyridazin-3-ones via reduction with hydrazine hydrate

A novel and simple protocol: the direct amination of 4,5-dichloropyridazinones can be carried out in hydrazine hydrate under mild conditions. 4-Chloro-5-hydrazinopyridazin-3-ones serves as a key intermediate in this reduction.

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Pyridazines. Part 34: Retro-ene-assisted palladium-catalyzed synthesis of 4,5-disubstituted-3(2H)-pyridazinones

The efficient one-pot bis-functionalization of the 4,5-positions of the 3-pyridazinone ring has been performed using Suzuki, Sonogashira and Stille cross-coupling reactions assisted by a retro-ene fragmentation. This route allows access in a shorter synthetic sequence to several pharmacologically useful 3(2H)-pyridazinones.

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Process for the preparation of a 3(2H)-pyridazinone-4- substituted amino 5-chloro derivative

The invention relates to novel processes for the preparation of 5-chloro-4-{3-[N-[2-(3,4-dimethoxyphenyl)-ethyl]-N-methylamino]-propylamino-3(2H) pyridazinone of formula (I) and the pharmaceutically acceptable acid addition salts thereof. An important feature of the invention is using 3,4,5-trichloropyridazone as starting substance of the synthesis.

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Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Product Details of 932-22-9, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 932-22-9, in my other articles.

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Synthesis and photochemical properties of trans-2-(2-aryl- or heteroarylvinyl)-4,5-dichloropyridazin-3(2H)-ones

(Figure Presented) trans-2-(2-Aryl- or heteroarylvinyl)-4,5- dichloropyridazin-3(2H)-ones 3 were synthesized from 4,5-dichloropyridazin-3(2H) -one via 2 step. The photochemical behavior of 3 in THF, methylene chloride, acetonitrile and methanol is dependent on the kind of aryl or heterocyclic ring and the solvent polarity.

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More research is needed about 4,5-Dichloro-3(2H)-pyridazinone

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Pyridazinones as antagonists of alpha4 integrins

The present invention relates to certain novel compounds of Formula (I): methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of integrin mediated disorders.

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Archives for Chemistry Experiments of 4,5-Dichloro-3(2H)-pyridazinone

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Reaction of 4,5-dichloropyridazin-6(1H)-ones with acyl and phosphinoyl isocyanates

4,5-dichloropyridazin-6(1H)-one, containing an unsubstituted NH group, reacts with aroyl isocyanates to form N- and O- addition products, whose ratio depends on the electrophilicity of the isocyanate. 1-hydroxymethyl-4,5-dichloropyridazin-6-one reacts with acyl or dialkoxyphosphinoyl isocyanates to give only the corresponding 2-aminocarbonyloxymethyl-4,5-dichloropyridazin-6-ones.

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Properties and Exciting Facts About 4,5-Dichloro-3(2H)-pyridazinone

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3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it

A 3(2H)pyridazinone of the formula: STR1 wherein R1 is hydrogen, methyl, C3 -C6 alkenyl, C5 or C6 cycloalkyl, benzyl, phenyl, –(CH2)m CO2 R3 (wherein R3 is hydrogen or C1 -C5 alkyl, and m is an integer of from 1 to 4), –(CH2)n A (wherein A is –OH or –N(R4)2 wherein R4 is C1 -C3 alkyl, and n is an integer of from 2 to 6) or –CH2 CF3 ; R2 is chlorine or bromine; each of Y1 and Y2 which may be the same or different, is hydrogen, C1 -C5 alkyl, C2 -C8 alkenyl, halogen, –OR5 (wherein R5 is hydrogen, C1 -C8 alkyl or STR2 wherein q is an integer of from 1 to 4), –CO2 R6 (wherein R6 is hydrogen or C1 -C5 alkyl), –N(R7)2 (wherein R7 is C1 -C4 alkyl) or –SR8 (wherein R8 is C1 -C4 alkyl); and Y3 is C1 -C5 alkyl, C2 -C8 alkenyl, halogen, –OR5 (wherein R5 is as defined above), –CO2 R6 (wherein R6 is as defined above), –N(R7)2 (wherein R7 is as defined above) or –SR8 (wherein R8 is as defined above), or a pharmaceutically acceptable salt thereof.

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Related Products of 932-22-9, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 932-22-9, molcular formula is C4H2Cl2N2O, introducing its new discovery.

N-phenoxypropanol-N’-pyridazinyl ethylendiamines as beta-receptor blockers

Basically-substituted pyridazines of the formula: STR1 wherein R1, R2 and R3, independently of one another, denote hydrogen, halogen, hydroxyl, nitro, trifluoromethyl, alkyl, alkoxyalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, alkoxy, hydroxyalkoxy, alkoxy-alkoxy, alkenyloxy, alkynyloxy, cycloalkoxy, phenalkoxy, alkanoyl, alkanoylamino and –NH–CO–R9, R9 representing morpholino, piperidino or 1-pyrrolididinyl, or an optionally substituted ureido radical, R4 denotes hydrogen or lower alkyl and W denotes hydrogen, chlorine or bromine; and the acid-addition salts thereof are useful alone or in pharmaceutical preparations for treating cardiac complaints, circulatory complaints and high blood pressure. Several methods for preparing the basically-substituted pyridazines are also provided.

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