Category: 920-66-1

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 920-66-1, Name is 1,1,1,3,3,3-Hexafluoropropan-2-ol, molecular formula is C3H2F6O, belongs to pyridazines compound, is a common compound. In a patnet, author is Chelini, Alessia, once mentioned the new application about 920-66-1, Recommanded Product: 1,1,1,3,3,3-Hexafluoropropan-2-ol.

Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators

LDN-212320 (3) was found to be a potent EAAT2 activator at a translational level, restoring the normal clearance of glutamate and providing neuronal protection. Since the pharmacologic activation of EAAT2 represents a valuable strategy to relieve neuropathic pain, we synthesized novel activators (4a-f) of EAAT2. Among them 4f, analyzed in comparison with 3 by different paradigms in a rat model of oxaliplatin-induced neuropathic pain, showed the better antihypersensitive profile being able to fully counteract the oxaliplatin-induced neuropathy.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 920-66-1. The above is the message from the blog manager. Recommanded Product: 1,1,1,3,3,3-Hexafluoropropan-2-ol.

Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 920-66-1, Name is 1,1,1,3,3,3-Hexafluoropropan-2-ol, formurla is C3H2F6O. In a document, author is Soderstrom, Marcus, introducing its new discovery. Formula: C3H2F6O.

BF3 center dot SMe2 for Thiomethylation, Nitro Reduction and Tandem Reduction/SMe Insertion of Nitrogen Heterocycles

Herein, a general, solvent-free and straightforward thiomethylation of electron deficient heterocycles using BF3 center dot SMe2 as a dual thiomethyl source and Lewis acidic activator is presented. A range of heterocycles including pyrimidine, pyrazine, pyridazine, thiazole and purine derivatives were successfully substituted using this method. An unexpected reductive property of BF3 center dot SMe2 towards nitropyridines was also discovered including an intriguing tandem reduction/SMe insertion process in certain substrates. Notable features of the present work include its convenience and use of a non-malodorous reagent while the discovery of novel chemical transformations using BF3 center dot SMe2 provides fundamental new insights into the reactivity of this commonly employed reagent.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 920-66-1 help many people in the next few years. Formula: C3H2F6O.

Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem