The important role of 90766-97-5

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 90766-97-5, help many people in the next few years.HPLC of Formula: C10H7BrN2O

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. HPLC of Formula: C10H7BrN2O, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 90766-97-5, name is 5-Bromo-6-phenylpyridazin-3(2H)-one. In an article£¬Which mentioned a new discovery about 90766-97-5

Pyridazines. XV. Synthesis of 6-aryl-5-amino-3(2H)-pyridazinones as potential platelet aggregation inhibitors

Several 3(2H)-pyridazinones with amino groups at the 5-position of the pyridazine nucleus have been prepared. The 6-aryl-5-halo-3(2H)-pyridazinones obtained from mucochloric and mucobromic acid lead to the corresponding 5- alkylamino-3(2H)-pyridazinones, which were tested as platelet aggregation inhibitors.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 90766-97-5, help many people in the next few years.HPLC of Formula: C10H7BrN2O

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3129 – PubChem

 

Properties and Exciting Facts About 5-Bromo-6-phenylpyridazin-3(2H)-one

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 90766-97-5, help many people in the next few years.HPLC of Formula: C10H7BrN2O

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. HPLC of Formula: C10H7BrN2O, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 90766-97-5, name is 5-Bromo-6-phenylpyridazin-3(2H)-one. In an article£¬Which mentioned a new discovery about 90766-97-5

Pyridazines XVII: An efficient Palladium-catalyzed cross-coupling reaction for the synthesis of 5-substituted 6-phenyl-2(2H)-pyridazin-3-ones

(2H)-Pyridazin-3-ones substituted at 5-position were prepared via Palladium-catalyzed cross-coupling reactions starting from bromopyridazinones and several vinyl and alkynyl coupling reagents according to Stille, Heck and Sonogashira conditions. MOM was employed as efficacious protecting group.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3128 – PubChem

 

Awesome Chemistry Experiments For 5-Bromo-6-phenylpyridazin-3(2H)-one

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 90766-97-5, and how the biochemistry of the body works.Recommanded Product: 5-Bromo-6-phenylpyridazin-3(2H)-one

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 90766-97-5, name is 5-Bromo-6-phenylpyridazin-3(2H)-one, introducing its new discovery. Recommanded Product: 5-Bromo-6-phenylpyridazin-3(2H)-one

PYRIDAZINONE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS

Compounds of formula (I) described herein inhibit phosphoinositide 3-kinases (PI3K) and useful for the treatment of disorders associated with PI3K enzymes.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 90766-97-5, and how the biochemistry of the body works.Recommanded Product: 5-Bromo-6-phenylpyridazin-3(2H)-one

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3119 – PubChem

 

The important role of 90766-97-5

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90766-97-5, Name is 5-Bromo-6-phenylpyridazin-3(2H)-one, belongs to pyridazine compound, is a common compound. Computed Properties of C10H7BrN2OIn an article, once mentioned the new application about 90766-97-5.

5-Amino-6-phenyl-1,6-dihydropyridazin-3(2H)-one

In the title compound, C10H9N3O, the pyridazinone moiety is essentially planar and forms a dihedral angle of 49.5 (1) with the phenyl substituent. The molecular packing is stabilized by van der Waals interactions and hydrogen bonds.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3130 – PubChem

 

More research is needed about 90766-97-5

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.90766-97-5. In my other articles, you can also check out more blogs about 90766-97-5

90766-97-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.90766-97-5, Name is 5-Bromo-6-phenylpyridazin-3(2H)-one, molecular formula is C10H7BrN2O. In a Article, authors is Sotelo, Eddy£¬once mentioned of 90766-97-5

Pyridazine derivatives 32: Stille-based approaches in the synthesis of 5-substituted-6-phenyl-3(2H)-pyridazinones

A series of 6-phenyl-3(2H)-pyridazinones bearing different substituents in the 5-position of the pyridazinone ring were prepared using Stille-based approaches in the search for new platelet-aggregation inhibitors.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.90766-97-5. In my other articles, you can also check out more blogs about 90766-97-5

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3131 – PubChem

 

Analyzing the synthesis route of 90766-97-5

As the paragraph descriping shows that 90766-97-5 is playing an increasingly important role.

90766-97-5,90766-97-5, 5-Bromo-6-phenylpyridazin-3(2H)-one is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 5-bromo-6-phenylpyridazin-3(2H)-one (1.522 g, 6.06 mmol) in DMF (90 mL) was added tert-buty 2-(((ls,4s)-4-(tosyloxymethyl)cyclohexyl)methoxy)acetate (2.50 g, 6.06 mmol), potassium 2-methylpropan-2-olate (1.360 g, 12.12 mmol) and 18-crown-6 (0.320 g, 1.212 mmol). The reaction was stirred at 40 0C for 16 h, quenched with water (40 mL), extracted with EtOAc (4 x 50 mL), and washed with brine. The combined organic phases were dried over MgSO4, filtered, and concentrated to give a brown oil. The brown oil was purified by silica gel column chromatography to give the title compound as a yellow oil (1.346 g). LCMS mlz = 491.3 [M+Eta]+; 1H NMR (400 M Hz, CDCl3) delta ppm, 1.37-1.64 (m, 17H), 1.80-1.90 (m, IH), 2.23 (bs, IH), 3.42 (d, J= 7.07 Hz, 2H), 3.94 (s, 2H), 4.17 (d, J = 7.71 Hz, 2H), 7.44-7.49 (m, 4H), 7.50-7.55 (m, 2H).

As the paragraph descriping shows that 90766-97-5 is playing an increasingly important role.

Reference£º
Patent; ARENA PHARMACEUTICALS, INC.; TRAN, Thuy-Anh; HAYASHI, Rena; IBARRA, Jason B.; ULLMAN, Brett; ZOU, Ning; WO2010/77275; (2010); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem

 

Analyzing the synthesis route of 90766-97-5

As the paragraph descriping shows that 90766-97-5 is playing an increasingly important role.

90766-97-5,90766-97-5, 5-Bromo-6-phenylpyridazin-3(2H)-one is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 5-bromo-6-phenyl-2,3-dihydropyridazin-3-one (0.500 g, 1.99 mmol) and N,N-dimethylformamide dimethyl acetal (0.397 mL, 2.978 mmol) in DMF (20 mL) was refluxed for 2 h. The mixture was diluted with EtOAc and washed with water and then several times with brine. The organic phase was dried over sodium sulfate and the solvent was removed. The crude was purified by flash chromatography on silica gel Biotage cartridge (cyclohexane:EtOAc=90:10 to 50:50) to afford title compound as a white solid (0.279 g, 1.05 mmol, 53% yield). MS/ESI+ 265.0-267.0 [MH]+, Rt=0.92 min (Method A).

As the paragraph descriping shows that 90766-97-5 is playing an increasingly important role.

Reference£º
Patent; CHIESI FARMACEUTICI S.p.A.; BIAGETTI, Matteo; Capelli, Anna Maria; Guala, Matilde; (42 pag.)US2016/75710; (2016); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem

 

Downstream synthetic route of 90766-97-5

90766-97-5 5-Bromo-6-phenylpyridazin-3(2H)-one 2767911, apyridazine compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.90766-97-5,5-Bromo-6-phenylpyridazin-3(2H)-one,as a common compound, the synthetic route is as follows.

90766-97-5, To a solution of 5-bromo-6-phenyl-2,3-dihydropyridazin-3-one (0.700 g, 2.788 mmol) in DMF (12 mL), potassium carbonate (0.462 g, 3.345 mmol) was added followed by 2-bromopropane (0.314 mL, 3.345 mmol) and the resulting mixture heated at 60 C. for 2 h. The mixture was partitioned between EtOAc and water, the aqueous phase was extracted with EtOAc, and the combined organic layers were washed several times with brine. The organic phase was dried over sodium sulfate and the solvent was removed. The crude was purified by flash chromatography on silica gel Biotage cartridge (cyclohexane to cyclohexane_EtOAc=85:15) to afford title compound as a pale yellow solid (0.630 g, 2.149 mmol, 77% yield). MS/ESI+ 293.1-295.1 [MH]+, Rt=1.11 min (Method A).

90766-97-5 5-Bromo-6-phenylpyridazin-3(2H)-one 2767911, apyridazine compound, is more and more widely used in various.

Reference£º
Patent; CHIESI FARMACEUTICI S.p.A.; BIAGETTI, Matteo; Capelli, Anna Maria; Guala, Matilde; (42 pag.)US2016/75710; (2016); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem