Category: 90008-50-7

Application of 90008-50-7, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 90008-50-7, molcular formula is C7H11N3O, introducing its new discovery.

N,N-Dialkyl-N?-chlorosulfonylchloroformamidines 1 reacted with 2-aminopyridines 2 to give novel pyrido[1,2-b][1,2,4,6]thiatriazine dioxides 3 and pyrido[2,1-c][1,2,4,6]thiatriazine dioxides 4. Reaction of 1 with 3-aminopyridazines 5 afforded pyridazo[3,2-c][1,2,4,6]thiatriazine dioxides 6 and a pyridazo[2,3-b][1,2,4,6]thiatriazine dioxide 7. The compounds 6 and 7 are derivatives of new ring systems. CSIRO 2007.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 90008-50-7 is helpful to your research. Synthetic Route of 90008-50-7

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1986 – PubChem

 

Application of 90008-50-7, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 90008-50-7, Name is 6-Propoxypyridazin-3-amine, molecular formula is C7H11N3O. In a Patent，once mentioned of 90008-50-7

Novel imidazo[1,2-b]pyridazine compounds useful for controlling parasites in animals and methods of treatment of parasite infestation in animals using the compounds are disclosed. Formula (I).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 90008-50-7. In my other articles, you can also check out more blogs about 90008-50-7

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1984 – PubChem

 

90008-50-7, Name is 6-Propoxypyridazin-3-amine, belongs to pyridazine compound, is a common compound. Formula: C7H11N3OIn an article, once mentioned the new application about 90008-50-7.

Syntheses, pharmacological evaluation and molecular modelling of substituted 6-alkoxyimidazo<1,2-b>pyridazines as new ligands for the benzodiazepine receptor

A series of 2,3-disubstituted-6-alkoxyimidazo<1,2-b>pyridazines has been synthesized and evaluated for in vitro affinity for the benzodiazepine receptor (BZR). 3-(Benzamidomethyl or substituted benzamidomethyl)-6-methoxy-2-(3,4-methylenedioxyphenyl)imidazo<1,2-b>pyridazines were found to be the most potent BZR ligands (eg, 4a, IC50 7 nM; 4e, IC50 14 nM; 4v, IC50 8 nM).Imidazo<1,2-b>pyridazines unsubstituted in the 3-position, or containing bulkier alkoxy groups in the 6-position, were found to bind less strongly to the BZR.Selected compounds from the series wereidentified from in vitro GABA-shift experiments as BZR agonists.Molecular modelling has been employed to identify the common pharmacophoric points of lipophilic and hydrogen bonding, ligand-receptor interaction and areas of steric hindrance for these substituted imidazo<1,2-b>pyridazines at the BZR. – Keywords: imidazo<1,2-b>pyridazine; benzodiazepine receptor; structure-activity relationship; molecullar modelling

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1987 – PubChem

 

Application of 90008-50-7, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 90008-50-7, molcular formula is C7H11N3O, introducing its new discovery.

A revision of the alcoholysis and alkanethiolysis of 3-amino-6-chloropyridazine

The synthesis of 3-amino-6-alkoxy- and 3-amino-6-alkylthiopyridazines via nucleophilic aromatic substitution on 3-amino-6-chloropyridazine is described. In contrast to literature reports, no pressure tube is required to perform these reactions.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 90008-50-7 is helpful to your research. Application of 90008-50-7

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1988 – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 90008-50-7, name is 6-Propoxypyridazin-3-amine, introducing its new discovery. Computed Properties of C7H11N3O

2-Phenylimidazo[1,2-b]pyridazine derivatives highly active against Haemonchus contortus

A series of 2-phenylimidazo[1,2-b]pyridazine derivatives were synthesized and evaluated for their in vitro anthelmintic activity against Haemonchus contortus. The most active compounds had in vitro LD99 values of 30 nM, which is comparable to that of the benchmark commercial nematocide, Ivermectin.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 90008-50-7, and how the biochemistry of the body works.Computed Properties of C7H11N3O

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1985 – PubChem

 

90008-50-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.90008-50-7,6-Propoxypyridazin-3-amine,as a common compound, the synthetic route is as follows.

General procedure: A stirred mixture of 3-amino-6-propoxypyridazine 3 (4.50g, 29.4mmol), 2-bromo-1-[4-(2-methoxyethoxy)phenyl]ethanone 11 (8.03g, 29.4mmol) and EtOH (280mL) was heated at reflux for 2.5 hours. The mixture was cooled and NaHCO3 (2.50g, 30mmol) was added. The mixture was stirred at room temperature for 15 hours, heated at reflux for 1 hour, then cooled and evaporated. The residue was extracted with CHCl3 (150mL) and the extract washed with saturated, aqueous NaCl solution (50mL), dried (MgSO4) and evaporated. The residue was purified by flash chromatography over silica gel. Elution with 1-2% MeOH in CH2Cl2 afforded a green/brown solid. Treatment with decolourising charcoal and recrystallization from cyclohexane gave 6f (3.95g, 41%) as pale green crystals, m.p. 82.5-84C. 1H NMR (CDCl3) ? 1.06 (3H, t, J=7.2Hz), 1.75-1.94 (2H, m), 3.47 (3H, s), 3.74-3.81 (2H, m), 4.14-4.21 (2H, m), 4.27 (2H, t, J=6.6Hz), 6.68 (1H, d, J=9.3Hz), 7.00 (2H, d, J=8.8Hz), 7.76-7.88 (3H, m), 7.94 (1H, s). MS (APCI+) m/z 328 (M+H, 100%).

90008-50-7 6-Propoxypyridazin-3-amine 10511047, apyridazine compound, is more and more widely used in various fields.

Reference£º
Article; Ali, Abdelselam; Cablewski, Teresa; Francis, Craig L.; Ganguly, Ashit K.; Sargent, Roger M.; Sawutz, David G.; Winzenberg, Kevin N.; Bioorganic and Medicinal Chemistry Letters; vol. 21; 14; (2011); p. 4160 – 4163;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem