Category: 89180-50-7

Having gained chemical understanding at molecular level, chemistry graduates may choose to apply this knowledge in almost unlimited ways, as it can be used to analyze all matter and therefore our entire environment. Synthetic Route of 89180-50-7

The invention discloses substituted heteroaryl compounds and compositions thereof and their use. The compounds of formula (I) compound or type shown in (I) a compound represented by stereo isomers, tautomers, nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt or its prodrug. The invention also provides a pharmaceutical composition, the compounds and pharmaceutical compositions can be regulated protein kinase, particularly Aurora kinase and JAK kinase activity, for the prevention, treatment, treatment and reduce protein kinase, in particular JAK kinase activity mediated diseases or disorders. (by machine translation)

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2212 – PubChem

 

89180-50-7, Name is 5,6-Dichloropyridazin-4-amine, belongs to pyridazine compound, is a common compound. COA of Formula: C4H3Cl2N3In an article, once mentioned the new application about 89180-50-7.

New syntheses of oxazolo<4,5-d>pyridazine derivatives 7 and 11 were achieved by the cyclization of substituted N-pyridazin-5-ylformamide oximes 6 and 10.Under mild reaction conditions the transformations of the substituted amino group at position 2 of the oxazolo<4,5-d>pyridazine system 7 occured to produce the compounds 11, 14, and 15, while under more drastic reaction conditions the nucleophilic attack at carbon at position 2 followed by the ring opening of the oxazole part of the molecule was observed to give the compounds 13, 16, 17 and 18. – Keywords: Cyclization with C-O bond formation; Substituted N-pyridazin-5-ylformamidines and -formamide oximes; Oxazolo<4,5-d>pyridazines; Ring opening of oxazolo<4,5-d>pyridazines

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2215 – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 89180-50-7, name is 5,6-Dichloropyridazin-4-amine, introducing its new discovery. category: pyridazine

The 3H-imidazo[4,5-c]pyridazine, 1H-imidazo[4,5-d]pyridazine, and 1H-benzimidazole analogues of the potent anticonvulsant purine 9-(2-fluorobenzyl)-6-methylamino-9H-purine (1, 78U79) were synthesized and tested for anticonvulsant activity. The 3H-imidazo[4,5-c]pyridazines 8 and 9 were prepared in five stages from 3,4,5-trichloropyridazine (2). The 1H-imidazolo[4,5-d]pyridazine 15 was synthesized in four stages from 5-[(benzyloxy)methyl]-1,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one (10a). The benzimidazole analogues 18 and 20 were prepared from 2,6-dinitroaniline in three stages. These compounds were one-tenth or less as active as 1 in protecting rats against maximal electroshock-induced seizures.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2214 – PubChem

 

89180-50-7, Name is 5,6-Dichloropyridazin-4-amine, belongs to pyridazine compound, is a common compound. HPLC of Formula: C4H3Cl2N3In an article, once mentioned the new application about 89180-50-7.

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2213 – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C4H3Cl2N3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 89180-50-7, Name is 5,6-Dichloropyridazin-4-amine, molecular formula is C4H3Cl2N3

NOVEL COMPOUNDS

The present invention discloses novel compounds inhibiting LRRK2 kinase activity, the preparation processes thereof, the compositions containing them, as well as the use in treating diseases characterized by LRRK2 kinase activity, particularly Parkinson¿s disease and Alzheimer¿s disease

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C4H3Cl2N3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 89180-50-7

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2211 – PubChem

 

Related Products of 89180-50-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.89180-50-7, Name is 5,6-Dichloropyridazin-4-amine, molecular formula is C4H3Cl2N3. In a Patent，once mentioned of 89180-50-7

Substituted heteroaryl compounds and compositions and uses thereof (by machine translation)

The invention discloses substituted heteroaryl compounds and compositions thereof and their use. The compounds of formula (I) compound or type shown in (I) a compound represented by stereo isomers, tautomers, nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt or its prodrug. The invention also provides a pharmaceutical composition, the compounds and pharmaceutical compositions can be regulated protein kinase, particularly Aurora kinase and JAK kinase activity, for the prevention, treatment, treatment and reduce protein kinase, in particular JAK kinase activity mediated diseases or disorders. (by machine translation)

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 89180-50-7, and how the biochemistry of the body works.Related Products of 89180-50-7

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2212 – PubChem

 

Application of 89180-50-7, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 89180-50-7, 5,6-Dichloropyridazin-4-amine, introducing its new discovery.

Pyridazinylurea plant regulators

Pyridazinylurea plant regulators of the formula STR1 and acid addition salts thereof; wherein R is alkyl or cycloalkyl, R1 is hydrogen or alkyl, each X independently is halogen, alkoxy, alkylthi or alkylsulfonyl, and p is 0, 1 or 2.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 89180-50-7. In my other articles, you can also check out more blogs about 89180-50-7

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N2210 – PubChem

 

89180-50-7, 5,6-Dichloropyridazin-4-amine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,89180-50-7

5,6-dichloropyridazine-4-amine (4.01 g, 24.5 mmol)And hydrazine (80%[w/w]Aqueous solution, 26.20g, 419mmol)The mixture was stirred at 90 C for 3 hours.Then cool to room temperature,Add water (20mL),Then a yellow solid precipitates,The filtered cake was collected as a yellow solid (3.51 g, yield 90%).

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Reference£º
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Jiatuo Sciences Corporation; Xi Ning; Li Minxiong; Peng Ju; Li Xiaobo; Zhang Tao; Hu Haiyang; Chen Wuhong; Bai Changlin; Ke Donghua; Chen Peng; (217 pag.)CN109776522; (2019); A;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem