Category: 89089-18-9

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 89089-18-9, name is 3-Bromo-6-chloropyridazine, introducing its new discovery. Application In Synthesis of 3-Bromo-6-chloropyridazine

HETEROCYCLES USEFUL AS IDO AND TDO INHIBITORS

Provided are compounds of Formula (I) shown below using for treatment of diseases or disorders mediated by IDO and/or TDO, pharmaceutical compositions and methods of preparation thereof.

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Pyridazine | C4H4N2863 – PubChem

 

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OXO-HETEROCYCLICALLY SUBSTITUTED ALKYL CARBOXYLIC ACIDS AND USE THEREOF

The present application relates to novel alkylcarboxylic acids having an oxo-substituted azaheterocyclic partial structure, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

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Ortho-substituted benzyl esters of cyclopropanecarboxylic acids

Ortho-substituted benzyl esters of cyclopropanecarboxylic acids I STR1 where X is N or CH and A is one of the following cyclopropane radicals: STR2 where R1 is CN, C2 -C8 -alkyl, CF3, C3 -C8 -alkenyl, (C1 -C4 -alkoxycarbonyl, unsubstituted or substituted phenyl-C1 -C6 -alkyl or phenyl-C3 -C6 -alkenyl, ethoxyphenyl, 2- or 3-bromophenyl, 2- or 4-trifluoromethylphenyl, 2,4- or 2,6-difluorophenyl, 2-fluoro-6-chlorophenyl, 2,4- or 2,6-dimethylphenyl, 2,3,6-trichlorophenyl or trimethylsilyl, R2 is H or halogen, R3 is unsubstituted or substituted phenyl, R4 is CH3 or halogen and Hal is halogen, with the proviso that X is CH when R1 is CF3 or trimethylsilyl, are suitable as fungicides and for controlling pests.

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Pyridazine | C4H4N2853 – PubChem

 

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. HPLC of Formula: C4H2BrClN2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 89089-18-9, name is 3-Bromo-6-chloropyridazine. In an article£¬Which mentioned a new discovery about 89089-18-9

PROCESS FOR PRODUCING 1,2-CIS-2-FLUOROCYCLOPROPANE-1?CARBOXYLIC ESTER COMPOUND

Provided is an industrially applicable process for producing 1,2-cis-2-fluorocyclopropane-1-carboxylic ester. A process for producing a compound represented by formula (3): [wherein R1 represents, for example, a C1-C8 alkyl group], which process includes reacting a compound represented by formula (1) : [wherein X1 represents a hydrogen atom, a chlorine atom, a bromine atom, or an iodine atom; X2 represents a hydrogen atom, a chlorine atom, a bromine atom, or an iodine atom; X1 and X2 are not simultaneously hydrogen atoms; and R1 has the same meaning as defined in formula (3)] with a reducing agent represented by formula (2): ????????M1BHmR2n (2-1) or M2(BHmR2n)2?????(2-2) [wherein M1 represents an alkali metal atom; M2 represents an alkaline earth metal atom or a zinc atom; R2 represents, for example, a hydrogen atom; m represents an integer from 1 to 4; n represents an integer from 0 to 3; and the sum of m and n is 4] in the presence of an aprotic polar solvent, and a Lewis acid such as a halide of an atom selected from among, for example, boron, magnesium, and aluminum.

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DIAZEPAM DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS

The invention is concerned with novel bicyclic compounds of Formula (I), wherein n, m, p, A, L, R1, R2, R3, R4, R5, R6, R7, R7, R8, R9 and R10 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor and can be used as medicaments.

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Generation and Reactions of Lithiated tert-Butyl and 2,6-Di(tert-butyl)-4-methylphenyl Cyclopropanecarboxylates

tert-Butyl and 2,6-di(tert-butyl)-4-methylphenyl (BHT) cyclopropanecarboxylates (4, 6, 24, 25) are lithiated with LiN(i-Pr)2 and t-BuLi, respectively.Reactions with alkyl halides, aldehydes, acyl chlorides, and heteroelectrophiles give alpha-substituted BHT esters which can be cleaved (t-BuOK/H2O/THF) to the corresponding carboxylic acids or reduced (LiAlH4/THF) to the cyclopropanemethanols.

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 89089-18-9, name is 3-Bromo-6-chloropyridazine, introducing its new discovery. HPLC of Formula: C4H2BrClN2

N-[3-(2-CARBOXYETHYL)PHENYL]PIPERIDIN-1-YLACETAMIDE DERIVATIVES AND USE THEREOF AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE

The present application relates to novel substituted 2-(piperidin-1-yl)acetamide derivatives, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases.

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CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS

The present disclosure describes novel IDO inhibitors and methods for preparing them. The pharmaceutical compositions comprising such IDO inhibitors and methods of using them for treating cancer, infectious diseases, and other disorders are also described

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Recommanded Product: 89089-18-9, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 89089-18-9, name is 3-Bromo-6-chloropyridazine. In an article£¬Which mentioned a new discovery about 89089-18-9

HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES

The present invention relates to novel hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer’s Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, pancreatitius, Parkinson’s disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, metabolic syndrome disorders (e.g., Syndrome X), thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

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Pyridazine | C4H4N2832 – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 89089-18-9, name is 3-Bromo-6-chloropyridazine, introducing its new discovery. HPLC of Formula: C4H2BrClN2

HETEROCYCLIC COMPOUND

The present invention provides a heterocyclic compound having a HDAC inhibitory action, and useful for the treatment of central nervous system diseases including neurodegenerative disease, and the like, and a medicament comprising the compound. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.

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Pyridazine – Wikipedia,
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