Category: 66346-87-0

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N-heterocyclyl sulphonamide derivatives and their use as endothelin antagonists

The invention concerns pharmaceutically useful N-heterocyclyl sulphonamide derivatives, their pharmaceutically acceptable salts, processes for their manufacture, their use for antagonising one or more actions of endothelin in a human or other warm-blooded animal, their use in methods of treatment of diseases or medical conditions in which elevated or abnormal levels of endothelin play a significant causative role.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1073 – PubChem

 

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TRIAZOLO COMPOUNDS

The present invention relates to compounds of formula (I) and its use for the treatment of neurological disorders.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1077 – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 66346-87-0, name is 6-Chloro-5-methylpyridazin-3-amine, introducing its new discovery. Application In Synthesis of 6-Chloro-5-methylpyridazin-3-amine

2-Phenylimidazo[1,2-b]pyridazine derivatives highly active against Haemonchus contortus

A series of 2-phenylimidazo[1,2-b]pyridazine derivatives were synthesized and evaluated for their in vitro anthelmintic activity against Haemonchus contortus. The most active compounds had in vitro LD99 values of 30 nM, which is comparable to that of the benchmark commercial nematocide, Ivermectin.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N1096 – PubChem

 

66346-87-0, Name is 6-Chloro-5-methylpyridazin-3-amine, belongs to pyridazine compound, is a common compound. SDS of cas: 66346-87-0In an article, once mentioned the new application about 66346-87-0.

BISARYL-SULFONAMIDES

Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARgamma or PPARdelta. In particular, the compounds of the invention modulate the function of PPARgamma or PPARdelta. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1088 – PubChem

 

Reference of 66346-87-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66346-87-0, Name is 6-Chloro-5-methylpyridazin-3-amine, molecular formula is C5H6ClN3. In a Patent£¬once mentioned of 66346-87-0

IMIDAZOPYRIDAZINES USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY

The present invention relates to compounds useful as inhibitors of the PAR-2 signaling pathway. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of GPCRs in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such GPCRs; and the comparative evaluation of new inhibitors of the PAR-2 signaling pathway. The compounds of this invention have formula I: wherein the variables are as defined herein.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 66346-87-0

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1076 – PubChem

 

Related Products of 66346-87-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66346-87-0, Name is 6-Chloro-5-methylpyridazin-3-amine, molecular formula is C5H6ClN3. In a Patent£¬once mentioned of 66346-87-0

COMPOUNDS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS

The present invention provides compounds of formula (I) (I) wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof for use in the treatment, prevention and/or delay of progression of amyotrophic lateral sclerosis (ALS). Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N1084 – PubChem

 

Synthetic Route of 66346-87-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66346-87-0, Name is 6-Chloro-5-methylpyridazin-3-amine, molecular formula is C5H6ClN3. In a Patent£¬once mentioned of 66346-87-0

CONTROL OF PARASITES IN ANIMALS BY THE USE OF IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES

Novel imidazo[1,2-b]pyridazine compounds useful for controlling parasites in animals and methods of treatment of parasite infestation in animals using the compounds are disclosed. Formula (I).

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1081 – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: 6-Chloro-5-methylpyridazin-3-amine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 66346-87-0, Name is 6-Chloro-5-methylpyridazin-3-amine, molecular formula is C5H6ClN3

SUBSTITUTED IMIDAZO[1,2-b]PYRIDAZINES, SUBSTITUTED IMIDAZO[1,5-b]PYRIDAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted imidazo[1,2-b]pyridazine compounds, substituted imidazo[1,5-b]pyridazine compounds, related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson’s disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,2-b]pyridazine compounds described herein include substituted imidazo[1,2-b]pyridazine-3-carboxamide compounds and variants thereof.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1092 – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 66346-87-0, name is 6-Chloro-5-methylpyridazin-3-amine, introducing its new discovery. Computed Properties of C5H6ClN3

NOVEL COMPOUNDS

This invention relates to imidazopyridazine substituted piperidine derivatives and their use as pharmaceuticals.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 66346-87-0, and how the biochemistry of the body works.Computed Properties of C5H6ClN3

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1067 – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C5H6ClN3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 66346-87-0, Name is 6-Chloro-5-methylpyridazin-3-amine, molecular formula is C5H6ClN3

SUBSTITUTED AMINOIMIDAZOPYRIDAZINES

The present invention relates to substituted aminoimidazopyridazine compounds of general formula (I) : in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C5H6ClN3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 66346-87-0, in my other articles.

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1082 – PubChem