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Related Products of 41933-33-9, In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system. In a article, 41933-33-9, molcular formula is C11H8Cl2N2O, introducing its new discovery.

A 3(2H)pyridazinone of the formula: STR1 wherein R1 is hydrogen, methyl, C3 -C6 alkenyl, C5 or C6 cycloalkyl, benzyl, phenyl, –(CH2)m CO2 R3 (wherein R3 is hydrogen or C1 -C5 alkyl, and m is an integer of from 1 to 4), –(CH2)n A (wherein A is –OH or –N(R4)2 wherein R4 is C1 -C3 alkyl, and n is an integer of from 2 to 6) or –CH2 CF3 ; R2 is chlorine or bromine; each of Y1 and Y2 which may be the same or different, is hydrogen, C1 -C5 alkyl, C2 -C8 alkenyl, halogen, –OR5 (wherein R5 is hydrogen, C1 -C8 alkyl or STR2 wherein q is an integer of from 1 to 4), –CO2 R6 (wherein R6 is hydrogen or C1 -C5 alkyl), –N(R7)2 (wherein R7 is C1 -C4 alkyl) or –SR8 (wherein R8 is C1 -C4 alkyl); and Y3 is C1 -C5 alkyl, C2 -C8 alkenyl, halogen, –OR5 (wherein R5 is as defined above), –CO2 R6 (wherein R6 is as defined above), –N(R7)2 (wherein R7 is as defined above) or –SR8 (wherein R8 is as defined above), or a pharmaceutically acceptable salt thereof.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3195 – PubChem

 

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4-Amino(alkylamino)-5-chloro-2-substituted-3-oxo-2H-pyridazines and 5-amino(alkylamino, dialkylamino)-4-chloro-2-substituted-3-oxo-2H-pyridazines have been prepared by nucleophilic substitution reactions of 4,5-dichloro-2-substituted-3-oxo-2H-pyridazines with amines in aprotic solvent.Structure of the compounds prepared has been proved by IR and UV spectra.Fungicidal and herbicidal activity of the compounds prepared have been tested.None of the compounds prepared exceeds the standard Vitavax in the fungicidal activity tests.Compounds VIII and XII show equal or better activity on the Hill reaction as compared with the standard pyrazone.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3213 – PubChem

 

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Modeling chemical reactions helps engineers virtually understand the chemistry, optimal size and design of the system, and how it interacts with other physics that may come into play. Application of 41933-33-9

Novel pyridazino[4,5-b][1,4]oxazine-3,5-diones were synthesized from N-[2-(3,4-dimethoxyphenyl)-ethyl]-2-chloroacetamide (or 2-chloropropanamide) and 1-alkyl-5-halo-4-hydroxypyridazin-6-ones in good yield.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3203 – PubChem

 

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Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.Read on for other articles about 41933-33-9category: pyridazine

category: pyridazine, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 41933-33-9, Name is 2-Benzyl-4,5-dichloropyridazin-3(2H)-one, molecular formula is C11H8Cl2N2O. In a Patent,once mentioned of 41933-33-9

The invention encompasses imidazo[ 1,2-a]pyridine and imidazo[ 1,2-b]pyridazine derivatives which selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer’s disease.Pharmaceutical compositions and methods of use are also included.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3188 – PubChem

 

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Future efforts will undeniably focus on the diversification of the new catalytic transformations. These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. Keep reading other articles of 41933-33-9, and how the biochemistry of the body works.Synthetic Route of 41933-33-9

Synthetic Route of 41933-33-9, The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic and theoretical assessments of solvent structures and their interactions with reaction intermediates and transition states.

Ring contraction of 7-substituted 2-phenyl-4H-pyridazino<4,5-e><1,3,4>thiadiazin-8(7H)-ones (5a-d) to 5-substituted 3-phenyl-1H-pyrazolo<3,4-d>pyridazin-4(5H)-ones (7a-d), through base-induced extrusion of sulphur, is described.Similar reactions proceed, not only on the 4-acetyl derivatives (4a-d) in basic media, but on 5a and the 4-methyl derivative (6a) thermally.Probable mechanism of these reactions are discussed.A comparable approach to the ring contraction, photochemical cyclisation of 2-substituted 5-(1-alkyl-2-benzylidenehydrazino)-4-chloro-3(2H)-pyridazinones (9a-e) to the corresponding 1-alkylpyrazolo<3,4-d>-pyridazinone derivatives (8a-e) is also performed.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3210 – PubChem

 

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Disclosed herein are antibacterial and antimicrobial compositions and methods of use. Also disclosed are screening assays for identification of an agent that specifically inhibits DsbB or bVKOR. Such methods are useful, for example, in identifying antibacterial and antimicrobial agents and compositions.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3189 – PubChem

 

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Related Products of 41933-33-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 41933-33-9, Name is 2-Benzyl-4,5-dichloropyridazin-3(2H)-one,introducing its new discovery.

This paper presents the synthesis of some alkyl or aryl pyridazinyl ethers from 2-alkyl-4-halo-5-hydroxy-and 2-alkyl-4,5-dichloropyridazin-3(2H)-ones or 3,6-dichloropyridazine. Reaction of 2-alkyl-4-halo-5-hydroxypyridazin-3(2H)-ones 1 with 1,2-dibromoethane or 1,3-dibromopropane gave the corresponding monopyridazin-5-yl ethers 2 and alpha,omega-[di(pyridazin-5-oxy)]alkanes 3. Treatment of 4 with 4-substituted-phenol afforded 5-(4-substituted-phenoxy)-2- (4-substituted-phenoxymethyl) derivatives 5. Reaction of 2-alkyl-4,5-dichloro derivatives 7 with 1 gave the corresponding di(pyridazin-5-yl) ethers 8 in good yields. Compound 10 was reacted with catechol to give monopyridazin-3-yl ether 11 and/or di(pyridazin-3-yl) ether 12. Also we described the results for the reaction of 2-alkyl-4-chloro-5-(4-substituted-phenoxy)pyridazin-3(2H)-ones with nucleophiles.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3204 – PubChem

 

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The present invention is directed to pyridazinone compounds of formula (I) and furan compounds of formula (II), pharmaceutical compositions of compounds of formula (I) and (II), kits containing these compounds, methods of syntheses, and a method of treatment of a proliferative disease in a subject by administration of a therapeutically effective amount of a compound of formulae (I) or (II). Both classes of compounds were identified through screening of a collection of small molecule libraries.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N3192 – PubChem

 

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Reference of 41933-33-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 41933-33-9, Name is 2-Benzyl-4,5-dichloropyridazin-3(2H)-one,introducing its new discovery.

A novel ring contraction for the conversion of 2,7-disubstituted 10H-dipyridazino<4,5-b:4',5'-e><1,4>thiazine-1,6-(2H,7H)-diones (4’a-c) into the corresponding 2,6-disubstituted 9H-dipyridazino<4,5-b:4',5'-d>pyrrole-1,5(2H,6H)-diones (7’a-c), through a base-induced extrusion of sulfur, is described.Heating of 4’a-c in dimethylformamide in the presence of potassium carbonate smoothly afforded 7’a-c, respectively, in good yields, although neither 2,8-dimethyl-10H-dipyridazino<4,5-b:4',5'-e><1,4>thiazine-1,9(2H,8H)-dione (5’a), nor 3,7-dimethyl-10H-dipyridazino<4,5-b:4'5'-e><1,4>thiazine-4,6(3H,7H)-dione (6’a) was susceptible to similar reaction conditions.The mechanism of the ring contraction, which may involve an intermediate (anion, C-) containing a thiirane ring, is also discussed.Keywords – pyridazine; dipyridazino<1,4>thiazine; dipyridazino<4,5-b:4'5'-d>pyrrole; sulfur extrusion; ring contraction; Smiles rearrangement; photochemical cyclization.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3209 – PubChem

 

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Safety of 2-Benzyl-4,5-dichloropyridazin-3(2H)-one, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 41933-33-9, Name is 2-Benzyl-4,5-dichloropyridazin-3(2H)-one, molecular formula is C11H8Cl2N2O

The present invention relates to a pyridazinone derivative which can be used as a caspase inhibitor, process for the preparation thereof, and pharmaceutical composition for inhibiting caspase comprising the same.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N3191 – PubChem