Category: 19064-65-4

Application of 19064-65-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 19064-65-4, 3-Methoxypyridazine, introducing its new discovery.

This invention relates to 1-pyridazinyl-hydroxyimino-3-phenyl-propanes of the formula (I) wherein R1 to R7 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and may therefore be useful as medicaments for the treatment of diseases such as type II diabetes.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N252 – PubChem

Related Products of 19064-65-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.19064-65-4, Name is 3-Methoxypyridazine, molecular formula is C5H6N2O. In a Article，once mentioned of 19064-65-4

The monomethoxyl derivatives of various ?-electron deficient N-heteroaromatics reacted with phenylacetonitrile in tetrahydrofuran in the presence of sodium hydride to give alpha-phenyl-N-heteroareneacetonitriles in the yields ranging from 45 to 78percent.On the contrary, the reaction of these methoxyl derivatives with ethyl cyanoacetate or malononitrile under similar conditions was restricted within narrow limits.The synthesis of benzoyl-N-heteroaromatics by the air-oxidation of alpha-phenyl-N-hetroareneacetonitriles was described additionally.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N273 – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of 3-Methoxypyridazine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 19064-65-4, Name is 3-Methoxypyridazine, molecular formula is C5H6N2O

The present invention relates to pyrrolopyridazine inhibitors of IRAK4 of formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N257 – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: 3-Methoxypyridazine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 19064-65-4, Name is 3-Methoxypyridazine, molecular formula is C5H6N2O

Pyridazines have been allowed to react with tetracyanoethylene oxide to give pyridazinium N-dicyanomethylides, which are subjected to vicarious nucleophilic substitution to afford the corresponding 4-substituted derivatives in moderate to good yields. The dicyanomethylene group is readily eliminated by a radical reaction, and 4-substituted pyridazines are obtained.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N263 – PubChem

Reference of 19064-65-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 19064-65-4, Name is 3-Methoxypyridazine,introducing its new discovery.

Compounds of the following formula: wherein A, D, Q, T, U, V, W, X, Y, Z, R1, and —- are as defined herein. This invention also relates to a method of inhibiting tubulin polymerization, or treating cancer or an angiogenesis-related disorder with one of these compounds.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N255 – PubChem

Synthetic Route of 19064-65-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 19064-65-4, 3-Methoxypyridazine, introducing its new discovery.

This invention relates to novel compounds having the structural formula I below: and their pharmaceutically acceptable salts, tautomers or in vivo-hydrolysable precursors, compositions and methods of use thereof, wherein RI, R2, R3, R4, RS, and R are defined in the specification. These novel compounds provide a treatment or prophylaxis of anxiety disorders, schizophrenia, cognitive disorders, and/or mood disorders

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N251 – PubChem

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Described herein are phenoxy-pyridazinyl-pyrimidine or phenoxy-pyrimidinyl-pyrimidine compounds and pharmaceutically acceptable salts thereof for use in the treatment of Ire1-mediated diseases and cancer.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N249 – PubChem

Electric Literature of 19064-65-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 19064-65-4, 3-Methoxypyridazine, introducing its new discovery.

The effect of long term degradation on soil black carbon (BC) is important for correctly interpreting the role of BC in the global carbon cycle and in biochar studies. To address this, we studied three soil profiles (0?2 m depth, > 9000 yr) in undisturbed Brazilian Cerrado vegetation naturally affected by wildfires. The molecular composition of several soil organic matter (OM) pools was studied using analytical pyrolysis. Other analyses included general chemical and physical characteristics and micromorphology. The soil OM fractions included the free light fraction (FLF; particulate OM), the occluded light fraction (OLF; particulate OM within aggregates), the 0.1 M NaOH extractable OM (EXT; comparable with the combined humic acid and fulvic acid fractions) and the remaining residue (RES; treated with HF/HCl; comparable with the humin fraction). Although each fraction represents a continuum of material, they were assigned a different degradation level. The light fractions represent relatively intact BC (i.e. charcoal) of which the OLF is more degraded than the FLF, the EXT contains more decomposed material and the RES represents residual OM that is difficult to decompose. The largest contribution to the total soil OM was from RES and EXT, together accounting for > 80% of the total soil C. The relative contribution from BC-associated pyrolysis products was generally large for all fractions (between 5% and 57%) and showed an increase with depth in the OLF and RES. Based on factor analysis exclusively applied to BC-associated pyrolysis products from all four OM fractions, two BC degradation indices were extracted: Index 1, reflecting depolymerization and relative enrichment of N, and Index 2, reflecting a relative increase in condensed structures. Both indices gradually increased with depth for all fractions, except FLF. Based on these indices, we selected some simple ratios that showed good correlation with them (r2 > 0.7). For Index 1, reflecting depolymerization, adequate ratios for all fractions included benzene/indene and benzene/C1 naphthalenes. For Index 2, reflecting the relative accumulation of condensed BC, adequate ratios for all fractions included biphenyl/C2-benzene, fluorene/C2-benzene and 4-ring PAHs/C2-benzene.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N265 – PubChem

Related Products of 19064-65-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.19064-65-4, Name is 3-Methoxypyridazine, molecular formula is C5H6N2O. In a Patent，once mentioned of 19064-65-4

New imidazo[1,2-b]pyridazine and imidazo[4,5-b]pyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N254 – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Product Details of 19064-65-4, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 19064-65-4

Ring-closing olefin metathesis (RCM) has been applied to the efficient synthesis of densely and diversely substituted pyridine and pyridazine frameworks. Routes to suitable metathesis precursors have been investigated and the scope of the metathesis step has been probed. The metathesis products function as precursors to the target heteroaromatic structures via elimination of a suitable leaving group, which also facilitates earlier steps by serving as a protecting group at nitrogen. Further functionalisation of the metathesis products is possible both prior to and after aromatisation. The net result is a powerful strategy for the de novo synthesis of highly substituted heteroaromatic scaffolds.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N261 – PubChem