Category: 16401-70-0

Related Products of 16401-70-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.16401-70-0, Name is N-Methylpyridazin-4-amine, molecular formula is C5H7N3. In a Patent，once mentioned of 16401-70-0

The present invention provides compounds of formula (I) wherein A, X, Y, R1 and R2 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 16401-70-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N247 – PubChem

 

Related Products of 16401-70-0, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 16401-70-0, Name is N-Methylpyridazin-4-amine,introducing its new discovery.

Certain disubstituted 3,8-diaza-bicyclo[4.2.0]octane and 3,6-diazabicyclo [3.2.0]heptane are described, which are useful as orexin inhibitors. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 16401-70-0, and how the biochemistry of the body works.Application of 16401-70-0

Referenceï¼?br>Pyridazine – Wikipedia,
Pyridazine | C4H4N244 – PubChem

 

Electric Literature of 16401-70-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 16401-70-0, molcular formula is C5H7N3, introducing its new discovery.

FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS

Disubstituted 3,8-diaza-bicyclo[4.2.0]octane and 3,6-diazabicyclo [3.2.0]heptane compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 16401-70-0 is helpful to your research. Electric Literature of 16401-70-0

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N245 – PubChem

 

16401-70-0, Name is N-Methylpyridazin-4-amine, belongs to pyridazine compound, is a common compound. Formula: C5H7N3In an article, once mentioned the new application about 16401-70-0.

GYRASE INHIBITORS

Novel gyrase inhibitors and related compositions and methods are useful for impeding bacterial growth. Compounds of Formula (I), are disclosed: Formula (I), wherein Y is N or CH; Z is N or CR5; R5 is H, a substituted or unsubstituted hydrocarbyl residue (1-3C) containing 0-2 heteroatoms selected from O, S and N, or is an inorganic residue; L is O, S, NR7, or CR8R9; R7 is H or C1-3 alkyl; R8 and R9 are each independently H or C1-3 alkyl; R2 is H, a hydrocarbyl residue (1-40C) containing 0-10 heteroatoms selected from O, S and N optionally substituted with an inorganic residue; R4 is H, an inorganic residue, or a hydrocarbyl residue (1-30C) containing 0- 12 heteroatoms selected from O, S and N and containing 0-10 inorganic residues, wherein R5 and R4 together may join to form a fused ring; and R6 is selected from the group consisting of H, C1-5 alkyl, C2-5 alkenyl, C2-5 alkynyl, halo C1-5 alkyl, halo C2-5 alkenyl, halo C2-5 alkynyl, C1-5 hydroxyalkyl, C1-5 alkyl chloride, C2-5 alkenyl chloride, and C2-5 alkynyl chloride; or a pharmaceutically-acceptable salt, ester, or prodrug thereof.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 16401-70-0

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N246 – PubChem

 

Electric Literature of 16401-70-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 16401-70-0, molcular formula is C5H7N3, introducing its new discovery.

Amino-substituted tricyclic derivatives and methods of use

Compounds of formula (I) wherein A and B are amine-substituted sidechains, Y1 and Y2 form various tricyclic cores, Xa and Xb are C, CH, or N, as defined herein, and Rx is an optional substituent. Compounds and compositions of formula (I) are contemplated as well as methods for treating conditions or disorders prevented by or ameliorated by alpha7nAChR ligands that encompass compounds of formula (I) and other tricyclic derivatives. Methods of using amino-substituted tricyclic derivatives also are described herein.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 16401-70-0 is helpful to your research. Electric Literature of 16401-70-0

Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N248 – PubChem

 

16401-70-0, N-Methylpyridazin-4-amine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

200 mg (1.2 mmol) of 2-chlorothiazole-4-carboxylic acid and 96.1 mg (0.9 mmol) of pyridazin-4-yl-amine were dissolved in 6 ml dimethyl formamide. 0.15 ml. (1.1 mmol) of triethyl amine followed by 382 mg (0.73 mmol) of 1 H-Benzotriazol-1- yloxytri-pyrrolidinophosphonium hexafluorophosphate (PyBOP) were added and the reaction mixture was stirred at room temperature for 16 h. Brine was added and the reaction mixture was extracted three times with dichloromethane. The combined organic layers were dried over sodium sulfate, filtered and the solvent was removed under reduced pressure. The obtained residue was purified by flash column chromatography (silica, gradient elution cyclohexane? ethyl ace- tate? methanol) to give 200 mg (61 %, 95% purity) of the title compound., 16401-70-0

The synthetic route of 16401-70-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; BASF SE; Le VEZOUET, Ronan; SOeRGEL, Sebastian; DEFIEBER, Christian; GROss, Steffen; KOeRBER, Karsten; CULBERTSON, Deborah, L.; ANSPAUGH, Douglas, D.; WO2011/3796; (2011); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem

 

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.16401-70-0,N-Methylpyridazin-4-amine,as a common compound, the synthetic route is as follows.

To a solution of N-methylpyridazin-4-amine (83 mg, 0.76 mmol), triethylamine (0.42 ml, 3.04 mmol)and a catalytic amount of DMAP in 15 ml THE was added a solution in CH2Cl2 (5 ml) of 1-(6-chloro-3-methyl-2-pyridyl)-5-methyl-pyrazole-4-carbonyl chloride (0.21 g, 0.76 mmol), prepared from thecorresponding acid (oxalyl chloride 5 eq., CH2Cl2, cat. DMF, 40C,5 h). The mixture was stirred at rtovernight. After evaporation of the solvents, the residue was taken up in ethyl acetate and washedwith a solution of sodium bicarbonate. After drying (MgSO4) and evaporating the organic phase, theresidue was purified by flash chromatography to give the title compound as white crystals. Mp: 190-4C, LCMS: 0.69 min, 343-5 (MH)., 16401-70-0

As the paragraph descriping shows that 16401-70-0 is playing an increasingly important role.

Reference£º
Patent; SYNGENTA PARTICIPATIONS AG; HALL, Roger Graham; EDMUNDS, Andrew; JEANGUENAT, Andre; WO2014/166795; (2014); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem

 

16401-70-0, N-Methylpyridazin-4-amine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,16401-70-0

600 mg (2.8 mmol) of S-tert-Butylcarbamoyl-isoxazole^-carboxylic acid were suspended in 20 ml. of toluene and two drops of dimethylformamide were added to the mixture. 0.26 ml. of thionylchloride (3.5 mmol) were added at room temperature and the reaction mixture was stirred at 65 0C for two hours. After removal of the solvent, toluene was added and the evaporation was repeated. The obtained residue was then dissolved in 10 ml. of dichloromethane and the solution was added dropwise to a solution containing 247 mg methyl-pyridazin-4-ylamine (2.3 mmol) and 0.43 ml triethyl amine (3.1 mmol) in 40 ml dichloromethane. The mixture was stirred at room temperature for 16 h and the solvent was removed under vaccum. The obtained residue was purified by flash column chromatography (silica, gradient elution cyclohexane? ethyl acetate? methanol) to give 180 mg (20%, 95% purity) of the title compound.

16401-70-0 N-Methylpyridazin-4-amine 23080684, apyridazine compound, is more and more widely used in various.

Reference£º
Patent; BASF SE; VEZOUET, Ronan Le; SOeRGEL, Sebastian; DEFIEBER, Christian; GROss, Steffen; KOeRBER, Karsten; CULBERTSON, Deborah, L.; ANSPAUGH, Douglas, D.; WO2011/3793; (2011); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem