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New pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs were synthesized and their inhibitory activities against DYRK1A, CDK5/p25, GSK3alpha/beta and p110-alpha isoform of PI3K evaluated using harmine as reference. Both furan-2-yl 10 and pyridin-4-yl 19 from the two different series, exhibited submicromolar IC50 against DYRK1A with no activities against the three other kinases. In addition, compound 10 exhibited antiproliferative activities in the Huh-7, Caco2 and MDA-MB-231 cell lines.

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Pyridazine | C4H4N2803 – PubChem

Related Products of 15456-86-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione, molecular formula is C4H3BrN2O2. In a Patent，once mentioned of 15456-86-7

Tricyclic nitrogen containing compounds),of formula (I) or a pharmaceutically, acceptable salt, solvate and/or N-oxide thereof: and their use as antibacterials.

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Pyridazine – Wikipedia,
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Modeling chemical reactions helps engineers virtually understand the chemistry, optimal size and design of the system, and how it interacts with other physics that may come into play. Related Products of 15456-86-7

Substituted triazolo-pyridazine derivative compounds represented by wherein the variables are disclosed herein are selective ligands for GABA-A receptors, particularly for the alpha2 and/or alpha3 subunits.

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Electric Literature of 15456-86-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione, molecular formula is C4H3BrN2O2. In a Patent，once mentioned of 15456-86-7

Substituted triazolo-pyridazine derivative compounds represented by wherein the variables are disclosed herein are selective ligands for GABA-A receptors, particularly for the alpha2 and/or alpha3 subunits.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2793 – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. name: 4-Bromo-1,2-dihydropyridazine-3,6-dione. Introducing a new discovery about 15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione

Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials .

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Reference of 15456-86-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione, molecular formula is C4H3BrN2O2. In a Article，once mentioned of 15456-86-7

New pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs were synthesized and their inhibitory activities against DYRK1A, CDK5/p25, GSK3alpha/beta and p110-alpha isoform of PI3K evaluated using harmine as reference. Both furan-2-yl 10 and pyridin-4-yl 19 from the two different series, exhibited submicromolar IC50 against DYRK1A with no activities against the three other kinases. In addition, compound 10 exhibited antiproliferative activities in the Huh-7, Caco2 and MDA-MB-231 cell lines.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 15456-86-7

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Pyridazine – Wikipedia,
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Reference of 15456-86-7, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione,introducing its new discovery.

The invention relates to compounds of formula (I), wherein R1 is a group selected from hydrogen, alkyl, aryl, aryalkil, heteroaryl, heteroarylalkyl, alkylcarbonyl, arylcarbonyl, arylalkylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl, heterocycloalkoxycarbonyl, alkylsulfonyl, arylsulfonyl, arylalkylsulfonyl, phosphonic and Si(Ra)2Rb, Y is a group selected from HN?NH and N?R2, R3 is a hydrogen atom, an alkyl, cycloalkyl, aryl, arylalkyl group, R4 is hydrogen atom or an alkyl group, enantiomers, diastereoisomers and the salts thereof.

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Pyridazine – Wikipedia,
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Related Products of 15456-86-7, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione,introducing its new discovery.

Bicyclic nitrogen containing compounds and their use as antibacterials.

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Pyridazine – Wikipedia,
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Application of 15456-86-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione, molecular formula is C4H3BrN2O2. In a Article，once mentioned of 15456-86-7

The synthesis of 4-methoxy-, 4-amino-3-chloro-, and 4-amino-1-(2,3- dideoxy-beta-D-glycero-pentofuranosyl)pyridazin-6-one nucleosides, 6, 19 and 20 is described. The synthesis of 3,4-dichloropyridazin-6-one (10) was accomplished in 44% overall yield using bromomaleic anhydride (17) as the starting material. The condensation of the silylated base of 10 with the halogenose 12 in the presence of trimethylsilyl triflate as a catalyst afforded a mixture of 3,4-dichloro-1-(3,5-di-O-p-toluoyl-2-deoxy-beta-D- erythro-pentofuranosyl)pyridazin-6-one (13) in 67% and its alpha-anomer 14 in 12% yield, respectively. A series of 3′-sulfonate esters were prepared to explore the synthesis of 3-chloro-4-hydroxy-1-(3-azido-2,3-dideoxy-beta-D- erythro-pentofuranosyl)pyridazin-6-one (32) via 6,3-anhydronucleoside analogues. Compounds 15, 19 and 20 were evaluated against human immunodeficiency virus, human cytomegalovirus, and herpes simplex virus type 1 but were inactive.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2807 – PubChem

15456-86-7, Name is 4-Bromo-1,2-dihydropyridazine-3,6-dione, belongs to pyridazine compound, is a common compound. SDS of cas: 15456-86-7In an article, once mentioned the new application about 15456-86-7.

Tricyclic nitrogen containing compounds of the following Formula (I) and their use as antibacterials.

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Pyridazine – Wikipedia,
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