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The preparations and spectral data for nine new N,N’-chelating ligands (5)-(13), each consisting of a pyrazole group N-linked to an azine or azole, are described.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N1904 – PubChem

 

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A novel strategy for efficient synthesis of various substituted heterocycles as kinase-directed combinatorial libraries is described. The general scheme involves capture of various dichloroheterocycles onto solid support and further elaborations by aromatic substitution with amines at elevated temperature or by anilines, boronic acids, and phenols via palladium-catalyzed cross-coupling reactions, thus the scaffold itself is transformed into a diversity element within the combinatorial scheme. Libraries consisting of discrete and highly diverse heterocyclic small molecules constructed with these chemistries are currently being evaluated in a variety of cell and protein-based assays. Copyright

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Reference:
Pyridazine – Wikipedia,
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A series of azines featuring differently halogen and protic group substituted pyridine, pyrimidine and pyridazine compounds have been synthesized and studied in terms of their crystal structures in order to develop a better understanding of the links between structural conditions and molecular packing behavior. Complemented by the structure results of related compounds known from the literature, intermolecular contact relationships connected to the present substance types were found, having potential use in future crystal engineering of similar compounds. This primarily involves the formation of N?I contacts aside from specific halogen?halogen and hydrogen bond type interactions.

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Pyridazine – Wikipedia,
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Organometallic complexes of practically unsubstituted (non-chelating) azines and their benzannulated derivatives, possible N-heterocyclic carbenes containing at least one double bond, and boron-, boron?nitrogen, silicon-, tri- and hexaphosphorus analogs of azines are considered in the view of their synthetic availability, coordination modes, and possible application in catalysis and materials chemistry.

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Reference:
Pyridazine – Wikipedia,
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The invention discloses a heat-activated delay fluorescent material, including formula (I) indicated by the structure: Wherein the D1 and D2 of the electron donor is different from each other. In addition, the invention also discloses an organic light emitting diode display device, includes an anode, a cathode and is located between the anode and the cathode of the organic functional layer, the organic function layer comprises formula (I) structure of a heat-activated delay fluorescent material. (by machine translation)

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Pyridazine – Wikipedia,
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The reaction of [RuX3(AsPh3)3] and N,N-disubstituted pyridazine-3,6-diamine in benzene under reflux afford novel binuclear, halo-bridged, ruthenium(III) complexes with the general formula [Ru2(AsPh3)2(mu-X)2X 4(L)] (X = Cl or Br; L = N,N-disubstituted pyridazine-3,6-diamine). All the complexes have been characterized by elemental analysis, spectral (UV-Vis, EPR) and electrochemical methods (CV, DPV). The electronic spectra of the complexes indicate the presence of d-d and intense LMCT transitions in the visible region. The molecular structure of one of the complexes (2) has been determined by X-ray crystallography, which indicates the bridging coordination of the pyridazine in these binuclear complexes. In complex (2) each metal has a distorted octahedral NCl4As coordination sphere constituted by the two exogenous bridging chlorides. The complexes are paramagnetic (low spin, d5) in nature and all the complexes at 77 K show rhombic distortion around the ruthenium ion with three different ‘g’ values (gx ? gy ? gz). All the complexes exhibit two quasi-reversible one electron reductive responses (RuIII-Ru III/RuII-RuIII; RuII-Ru III/RuII-RuII) within the E1/2 range of -0.68 to -0.78 V and -1.25 to -1.33 V, respectively, versus SCE.

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Pyridazine – Wikipedia,
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Theophylline derivatives with several groups linked at the 7-position were synthesized and their pharmacological activities were studied on guinea pig. Relaxant action in the tracheal muscle was increased in comparison with that of theophylline when the 3(2H)-pyridazinone system was linked to 7-(2-ethyl)-theophylline through the piperazine ring, but decreased when the 7-(2-ethyl)-theophylline was linked to 3(2H)-pyridazinone ring through an amino group.

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Pyridazine – Wikipedia,
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The present invention relates to microbicides for agricultural or horticultural use containing sulfonamide derivative of, for example, a formula (I):or a salt thereof,[wherein A1is (1) an aryl group which may be substituted or (2) a heterocyclic group which may be substituted, X1is (1) a chemical bond, (2) a methylene group which may be substituted, or (3) a vinylene group which may be substituted, B1is a five-membered heterocyclic group comprising nitrogen or sulfur atoms as the ring-constructing atoms except for carbon atoms and may be substituted or a condensed heterocyclic group which may be substituted, Z1is (1) a hydrocarbon group which may be substituted, (2) an acyl group which may be substituted, (3) formyl group, (4) an amino group which may be substituted, (5) a group represented by -N=CR1R2(wherein each of R1and R2is a hydrogen atom or a hydrocarbon group which may be substituted), (6) a cyclic amino group, (7) a group represented by -OR3(wherein R3is a hydrogen atom, a hydrocarbon group which may be substituted, an acyl group which may be substituted, formyl group or an alkylsulfonyl group which may be substituted) or (8) -S(O)nR4(wherein n stands for an integer from 0 to 2, R4stands for a hydrogen atom or a hydrocarbon group which may be substituted). The said compounds or the salts thereof are sulfonamide derivatives with microbicidal action, areuseful as excellent microbicides for agricultural or horticultural use, because they are safe, and they have little influence on human beings, farm animals, natural enemies, or the environment, and exert excellent control effects even on resistant microbes.

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Pyridazine – Wikipedia,
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The present invention provides a novel epoxy compound, which can be converted into a cured epoxy resin product having liquid crystal properties by curing with a curing agent. Since the cured epoxy resin product of the present invention exhibits good heat conductivity, it is also useful as an insulating material requiring high heat releasability such as a printed circuit substrate and the like.

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An efficient synthesis of cinchona alkaloid-derived ligands based on solvent-free microwave-assisted reaction was described. The coupling of 1,4-dichlorophthalazine or 3,6-dichloropyridazine with quinine, cinchonine or cinchonidine provide bis- or mono-cinchona alkaloid-derived ligands in moderate to good yields (52-89%) within 15 min under optimum microwave conditions.

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Reference:
Pyridazine – Wikipedia,
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