Category: 141-30-0

Application of 141-30-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.141-30-0, Name is 3,6-Dichloropyridazine, molecular formula is C4H2Cl2N2. In a Article，once mentioned of 141-30-0

3,6-Dichloropyridazine was ortho-lithiated by lithium 2,2,6,6-tetramethylpiperidide.The resulting lithio compound was reacted with carbonyl derivatives iodine, iodine and trimethylchlorosilane.An azaxanthone was synthesized.An unusual regioselectivity for the lithiation of 2,4-dichloropyrimidine was studied.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1931 – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: pyridazine. Introducing a new discovery about 141-30-0, Name is 3,6-Dichloropyridazine

The general and efficient synthesis of the title compounds, consisting of the (selective) replacement of chlorine in commercial alpha-chlorodiazines and cyanuryl chloride by the 3,7-dioxa-r-1-azabicyclo[3.3.0]oct-c-5-ylmethoxy group (Williamson method) is described. The stereochemistry of this new series of derivatives is analysed in terms of different conformational chirality exhibited in solution (1H NMR) versus solid state (X-ray diffractometry), meso against chiral forms, respectively. In solid state, the inclusion capacity of some chiral networks as well as their supramolecular aggregation is pointed out. A good correlation between rotameric behaviour of the c-5-di(s-tri)diazinyloxymethyl group in the two states is found.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 3,6-Dichloropyridazine, you can also check out more blogs about141-30-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1617 – PubChem

Application of 141-30-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.141-30-0, Name is 3,6-Dichloropyridazine, molecular formula is C4H2Cl2N2. In a Article，once mentioned of 141-30-0

We report an oxidative homocoupling of diheteroaryl or diarylmanganese reagents prepared by directed manganation using TMP2Mn·2MgCl2·4LiCl. The resulting diorganomanganese reagents can efficiently undergo an oxidative dimerization leading to the homocoupling products in good yields. Remarkably, a number of functional groups, as well as sensitive heterocycles are tolerated using this metalation-dimerization procedure.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1720 – PubChem

141-30-0, Name is 3,6-Dichloropyridazine, belongs to pyridazine compound, is a common compound. Quality Control of 3,6-DichloropyridazineIn an article, once mentioned the new application about 141-30-0.

Described herein are splice modifying compounds affecting splicing of mRNA, such as pre-mRNA, expressed from the FOXM1 gene, compositions comprising thereof, and methods using the same.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1442 – PubChem

Reference of 141-30-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.141-30-0, Name is 3,6-Dichloropyridazine, molecular formula is C4H2Cl2N2. In a Article，once mentioned of 141-30-0

The gas-phase molecular structures of 4,6-dichloropyrimidine, 2,6-dichloropyrazine and 3,6-dichloropyridazine have been determined by electron diffraction (GED) and ab initio calculations, and are compared to their respective parent compounds to demonstrate the effects of chlorination on ring geometry. The crystal structures of the three dichloro compounds are also reported; the intermolecular contacts leading to distortions in the solid phases have been identified.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1825 – PubChem

Application of 141-30-0, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 141-30-0, 3,6-Dichloropyridazine, introducing its new discovery.

This invention relates to chemical compounds which have selective thyromimetic activity. A compound of this invention is 3,5-dibromo-3”-[6-oxo-3(1H)-pyridazinylmethyl]-thyronine.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 141-30-0. In my other articles, you can also check out more blogs about 141-30-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1305 – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Application In Synthesis of 3,6-Dichloropyridazine, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 141-30-0, name is 3,6-Dichloropyridazine. In an article，Which mentioned a new discovery about 141-30-0

In continuation of a previous study on the modulation of pi-electron conjugation of oligo(triacetylene)s by insertion of central hetero-spacer fragments between two (E)-hex-3-ene-1,5-diyne ((E)-1,2-diethynylethene, DEE) moieties (Fig. 1), a new series of trimeric hybrid oligomers (14-18 and 22-24, Fig. 2) were prepared (Schemes 1-3). Spacers used were both electron-deficient (quinoxaline-based heterocycles, pyridazine) and electron-rich (2,2?-bithiophene, 9,9-dioctyl-9H-fluorene) chromophores. With 19-21 (Scheme 4), a series of transition metal complexes was synthesized as potential precursors for nanoscale scaffolding based on both covalent acetylenic coupling and supramolecular assembly. The UV/VIS spectra (Fig. 3) revealed that the majority of spacers provided heterotrimers featuring extended pi-electron delocalization. The new hybrid chromophores show a dramatically enhanced fluorescence compared with the DEE dimer 13 and homo-trimer 12 (Fig. 5). This increase in emission intensity appears as a general feature of these systems: even if the spacer molecule is non-fluorescent, the corresponding hetero-trimer may show a strong emission (Table 2). The redox properties of the new hybrid chromophores were determined by cyclic voltammetry (CV) and rotating-disk voltammetry (RDV) (Table 3 and Fig. 5). In each case, the first one-electron reduction step in the hetero-trimers appeared anodically shifted compared with DEE dimer 13 and homo-trimer 12. With larger spacer chromophore extending into two dimensions (as in 14-18, Fig. 2), the anodic shift (by 240-490 mV, Table 3) seems to originate from inductive effects of the two strongly electron-accepting DEE substituents rather than from extended pi-electron conjugation along the oligomeric backbone, as had previously been observed for DEE-substituted porphyrins.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1680 – PubChem

Electric Literature of 141-30-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.141-30-0, Name is 3,6-Dichloropyridazine, molecular formula is C4H2Cl2N2. In a article，once mentioned of 141-30-0

On the basis of ideas recently advanced regarding the origin of enantioselectivity in the OsO4 promoted dihydroxylation of olefins catalyzed by bis-cinchona alkaloid derivatives such as 1, specifically strong evidence for reaction via transition state assembly 2, the mono-quinidine derivative 3 was selected as a promising catalytic ligand.The experimental observation of high enantioselectivity promoted by 3 provides additional evidence in favor of transition-state 2.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 141-30-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1657 – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Computed Properties of C4H2Cl2N2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 141-30-0, name is 3,6-Dichloropyridazine. In an article，Which mentioned a new discovery about 141-30-0

The purpose of the present invention is to provide a compound that has excellent CDK4/6 inhibitory activity. The present invention is a compound represented by formula (I) or a pharmaceutically acceptable salt of the compound.

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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1455 – PubChem

Synthetic Route of 141-30-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 141-30-0, molcular formula is C4H2Cl2N2, introducing its new discovery.

A novel ratiometric fluorescence sensor for rapid and on-site visual detection of Cu2+ was designed and synthesized by integrating yellow-emission rhodamine fluorophore (RL) and red-emission CdTe@SiO2 QDs. The as-prepared nanohybrid fluorescence sensor shows dual-emissions at 537 nm and 654 nm under a single excitation at 500 nm in the presence of Cu2+. Owing to the strong chelating ability of RL toward Cu2+, the yellow fluorescence of RL could be selectively enhanced while the red fluorescence of CdTe QDs is almost unchanged, leading to an obvious fluorescence color change from red to yellow, which could be used for visual and ratiometric detection of Cu2+. This nanohybrid sensor exhibits excellent selectivity, sensitivity and anti-interference to Cu2+ detection and the detection limit is as low as 8.4 nM. Additionally, a simple device test strip for rapid and on-site detection of Cu2+ has been designed by immobilizing the RL-CdTe@SiO2 QDs on a common filter paper. This simple and effective paper-based sensor has a visual detection limit of 0.5 muM, showing its promising application for on-site and rapid sensing of Cu2+ in pollution water.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 141-30-0 is helpful to your research. Synthetic Route of 141-30-0

Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1642 – PubChem