35857-89-7, 6-Chloropyridazine-3-carbonitrile is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a deoxygenated mixture of 6-chloropyridazine-3-carbonitrile (100 mg, 0.717 mmol) , (4- (methylsulfonyl) phenyl) boronic acid (215 mg, 1.08 mmol) , and sodium carbonate (190 mg, 1.79 mmol) in dioxane (3 mL) and water (0.600 mL) was added PdCl2(dppf) (58 mg, 0.072 mmol) , and the resulting mixture was heated at 80 for 3 h under a nitrogen atmosphere. The mixture was cooled and filtered. The filtrate was concentrated and the residue was purified by column chromatography on silica gel (0-10MeOH/DCM) to afford the title compound. MS: m/z 260.0 (M + 1) .
As the paragraph descriping shows that 35857-89-7 is playing an increasingly important role.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; COOKE, Andrew J.; PITTS, Daniel; JOHNSON, Adam; BESHORE, Douglas C.; HURZY, Danielle; MITCHELL, Helen; FRALEY, Mark; MCCOMAS, Casey; SCHIRRIPA, Kathy; MERCER, Swati P.; NANDA, Kausik; MENG, Dongfang; WU, Jane; BABAOGLU, Kerim; LI, Chun Sing; MAO, Qinghua; QI, Zhiqi; (156 pag.)WO2016/54807; (2016); A1;,
Pyridazine – Wikipedia
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