Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Gaddam, Lakshmi Teja and a compound is mentioned, 5469-70-5, 3-Aminopyridazine, introducing its new discovery. 5469-70-5
Synthesis of carboxamide and sulfonyl carboxamide linked heterocycles under green conditions
Direct coupling of heteroaldehydes with heteroaryl amines / sulfonylamines is performed under green conditions using PEG-400 in the presence of oxidant CCl3CN/H2O2. The presence of electron withdrawing substituents on heteroaldehydes increased the yield. Further heteroaryl amines favor the reaction when compared with heteroaryl sulfonylamines.
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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N71 – PubChem