54709-94-3, 5-Methylpyridazin-3(2H)-one is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
54709-94-3, Example 386-Oxo-1,6-dihydro-pyridazine-4-carboxylic acid The title compound from Example 37 (0.90 g, 8.2 mmol) was stirred in concentrated sulfuric acid (13 mL) and heated to 45 C. Potassium permanganate (3.6 g, 12 mmol) was added portion wise over 30 min to avoid letting the temperature rise. The reaction was allowed to stir for a further 30 min at 45 C. The reaction was then cooled to room temperature and ice was added to the reaction mixture. The resulting precipitate was collected by vacuum filtration, washing with cold water and diethyl ether to give 0.98 g (87%) of the title compound as the a pale green solid.1H NMR (300 MHz, CDCl3): delta (ppm) 13.39 (broad s, 1H), 8.12 (s, 1H), 7.22 (s, 1H).
The synthetic route of 54709-94-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; AstraZeneca AB; NPS PHARMACEUTICALS, INC.; US2007/259860; (2007); A1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem