372118-01-9, Methyl 4,6-dichloropyridazine-3-carboxylate is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Compound 4,6-dichloropyridazine-3-carboxylic acid methyl ester 1a (100 mg, 0.483 mmol) and 6- (methylthio) pyridin-3-amine (101 mg, 0.724 mmol) were dissolved in ethanol (2 mL), It was heated to 110 C in a microwave reactor and stirred for 1 hour.After cooling to room temperature, the solvent was removed under reduced pressure, and the residue was purified by silica gel column chromatography (petroleum ether / ethyl acetate = 2/1 to 1/1),The target product 6-chloro-4-((6- (methylthio) pyridin-3-yl) amino) pyridazine-3-carboxylic acid methyl ester 13a (100 mg, yellow solid) was obtained,Yield: 66%.
372118-01-9, As the paragraph descriping shows that 372118-01-9 is playing an increasingly important role.
Reference£º
Patent; Beijing Nuochengjianhua Pharmaceutical Technology Co., Ltd.; Chen Xiangyang; Pang Yucheng; (142 pag.)CN110818641; (2020); A;,
Pyridazine – Wikipedia
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