With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34584-69-5,3,6-Dichloro-4,5-dimethylpyridazine,as a common compound, the synthetic route is as follows.
Preparation 8 Synthesis of 3-ethoxy-4,5-dimethyl-6-chloropyridazine 0.69g(0.03mol) of metallic sodium was dissolved in 100mlitre of absolute ethanol and then 5.31g(0.03mol) of 3,6-dichloro-4,5-dimethylpyridazine was added thereto and completely dissolved. The reaction solution was stirred for 4 hours at room temperature and then treated according to the same manner as Preparation 5 to obtain the title compound as a pale white crystal. Yield: 4.22g (75.4percent) Melting Point: 60-62¡ãC Recrystallizing solvent: ethanol NMR(CDCl3, delta): 1.42(t, 3H, CH3), 2.20((s, 3H, CH3), 2.32(s, 3H, CH3), 4.52(q, 2H, OCH2)
As the paragraph descriping shows that 34584-69-5 is playing an increasingly important role.
Reference£º
Patent; Seoul Pharm. Co., Ltd.; Kwon, Soon Kyoung; EP1058681; (2003); B1;,
Pyridazine – Wikipedia
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