Cu-Catalyzed Aerobic Oxidative Cyclization of Guanidylpyridines and Derivatives was written by Bartels, Bjorn;Bolas, Conor Gordon;Cueni, Philipp;Fantasia, Serena;Gaeng, Nicolas;Trita, Andrada Stefania. And the article was included in Journal of Organic Chemistry in 2015.Synthetic Route of C4H5N3 This article mentions the following:
A new method for the straightforward synthesis of 2-amino-[1,2,4]triazolo[1,5-a]pyridines and derivatives is presented. The target products are synthesized in high yields from guanidylpyridines and analogs via copper-catalyzed N-N coupling. The present methodol. shows a wide scope, tolerating not only different substituents on the pyridine ring but also different heterocylic rings such as pyrazines, pyrimidines, and pyridazines. In the experiment, the researchers used many compounds, for example, 3-Aminopyridazine (cas: 5469-70-5Synthetic Route of C4H5N3).
3-Aminopyridazine (cas: 5469-70-5) belongs to pyridazine derivatives. Pyridazines is a six-membered nitrogen-containing significant heterocycle. It has received considerable interest because of its useful applications as natural products, pharmaceuticals, and various bioactive molecules. Specifically, the pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, cardiotonic, vasodilator, antiarrhythmic, and hypocholesterolaemic.Synthetic Route of C4H5N3
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem