Highly efficient Pd-PEPPSI-IPr catalyst for N-(4-pyridazinyl)-bridged bicyclic sulfonamides via Suzuki-Miyaura coupling reaction was written by Sura, Mallikarhuna Reddy;Bijivemula, N. Reddy;Pogula, Sreekanth Reddy;Motakatla, Venkata Krishna Reddy;Madhvesh, Pathak;Peddiahgari, Vasu Govardhana Reddy. And the article was included in Applied Organometallic Chemistry in 2018.Product Details of 141-30-0 This article mentions the following:
A protocol for the Suzuki-Miyaura coupling of novel 2-(6-chloropyridazin-3-yl)-5-(aryl/heteroarylsulfonyl)-2,5-diazabicyclo[2.2.1]heptanes and heteroarylboronic acids to afford variety of coupled products was realized. Pd-PEPPSI-IPr catalyst was found to be a powerful and reusable catalyst under relatively mild reaction conditions. In the experiment, the researchers used many compounds, for example, 3,6-Dichloropyridazine (cas: 141-30-0Product Details of 141-30-0).
3,6-Dichloropyridazine (cas: 141-30-0) belongs to pyridazine derivatives. The pyridazine structure is a popular pharmacophore which is found within a number of herbicides such as credazine, pyridafol and pyridate. Pyridazine is bioavailable (especially in the CNS) and can reduce toxicity. Pyridazine is a component of several drug molecules, and the pyridazine pharmacophore has contributed to a variety of pharmacologically active compounds.Product Details of 141-30-0
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem