Photochemistry. II. Formation of methyl paraconates and dimethyl succinates from pyridazines was written by Tsuchiya, Takashi;Arai, Heihachiro;Igeta, Hiroshi. And the article was included in Chemical & Pharmaceutical Bulletin in 1971.Name: 1,2-Dihydro-4-methyl-3,6-pyridazinedione This article mentions the following:
Irradiation of 6-chloro-3(2H)-pyridazones, maleic hydrazides, and 3,6-dichloropyridazines in MeOH containing HCl, afforded γ-lactones, Me paraconates (I), and dimethyl succinates MeO2CCH2CH(R)CO2Me (II). A short time irradiation of 3,6-dichloropyridazines resulted in the formation of methylated pyridazines (III and IV), hydroxymethylated pyridazines (V), and methylated pyridazones (VI), along with the γ-lactones (I) and the succinates (II). The mechanism of the formation of the γ-lactones and the succinates was also discussed. In the experiment, the researchers used many compounds, for example, 1,2-Dihydro-4-methyl-3,6-pyridazinedione (cas: 5754-18-7Name: 1,2-Dihydro-4-methyl-3,6-pyridazinedione).
1,2-Dihydro-4-methyl-3,6-pyridazinedione (cas: 5754-18-7) belongs to pyridazine derivatives. Pyridazines are rare in nature, possibly reflecting the scarcity of naturally occurring hydrazines, common building blocks for the synthesis of these heterocycles. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Name: 1,2-Dihydro-4-methyl-3,6-pyridazinedione
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem