Tomasik, P. et al. published their research in Chemicke Zvesti in 1977 | CAS: 5469-70-5

3-Aminopyridazine (cas: 5469-70-5) belongs to pyridazine derivatives. The pyridazine derivatives are mostly present in biologically active compounds and are also present with different pharmacophores. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Safety of 3-Aminopyridazine

Reexamination of the application of linear free energy relationships to the azaheterocyclic systems. I. Substituent effects on the basicity of monocyclic azines was written by Tomasik, P.;Zalewski, R.. And the article was included in Chemicke Zvesti in 1977.Safety of 3-Aminopyridazine This article mentions the following:

The basicities of pyridines, pyrimidines, pyridazines, and pyrazines (180 compounds) were correlated with substituent effects by Hammett and Taft equations. Limitations of the LFER are discussed. In the experiment, the researchers used many compounds, for example, 3-Aminopyridazine (cas: 5469-70-5Safety of 3-Aminopyridazine).

3-Aminopyridazine (cas: 5469-70-5) belongs to pyridazine derivatives. The pyridazine derivatives are mostly present in biologically active compounds and are also present with different pharmacophores. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Safety of 3-Aminopyridazine

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem