Synthesis and characterization of some nitrogen containing heterocyclic derivatives via novel chalcones was written by Tupare, Shrikrishn D.. And the article was included in World Journal of Pharmaceutical Research in 2021.Electric Literature of C4H2Cl2N2 This article mentions the following:
A highly stable five-membered ring structures like 1, 3, 5-triphenyl 1H pyrazoles and its derivatives I [R = H, 2-NO2, 4-NO2] was prepared via novel chalcones II synthesized by aromatic ketone and aldehydes in alk. medium having heterocyclic moiety. These compounds were characterized using IR, 1H-NMR and mass spectra and elemental anal. As per literature, they possess some potent biol. activities. Therefore, antibacterial and antifungal activities were screened for these derivatives most of the compounds were found to be the most active against bacterial and fungal human pathogens. In the experiment, the researchers used many compounds, for example, 3,6-Dichloropyridazine (cas: 141-30-0Electric Literature of C4H2Cl2N2).
3,6-Dichloropyridazine (cas: 141-30-0) belongs to pyridazine derivatives. The pyridazine structure is also found within the structure of several drugs such as cefozopran, cadralazine, minaprine, pipofezine, and hydralazine. Specifically, the pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, cardiotonic, vasodilator, antiarrhythmic, and hypocholesterolaemic.Electric Literature of C4H2Cl2N2
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem