Pyridazines. XXI. Reaction of 1-methylpyridazinium salts with potassium cyanide was written by Kaneko, Chisato;Tsuchiya, Takashi;Igeta, Hiroshi. And the article was included in Chemical & Pharmaceutical Bulletin in 1973.Related Products of 19064-65-4 This article mentions the following:
The reaction of pyridazinium sulfates, prepared from the corresponding pyridazines and Me2SO4, with KCN was studied. The pyridazines (I, R = H, Me, MeO; R1 = R2 = H) gave dimers II and III and the pyridazinone IV. 3-Phenylpyridazines (I, R = Ph; R1 = R2 = H, Me) gave the 4-pyridazinenitriles (V) as the main product. Other pyridazines (e.g., I, R = R2 = H, R1 = Me; R = R2 = Me, R1 = H; R = MeO, R1 = H, R2 = Me) gave various cyano- and dicyanopyridazines. The mechanism of their formation were discussed. In the experiment, the researchers used many compounds, for example, 3-Methoxypyridazine (cas: 19064-65-4Related Products of 19064-65-4).
3-Methoxypyridazine (cas: 19064-65-4) belongs to pyridazine derivatives. Pyridazine-based compounds continued to be a great source of biologically active compounds as evidenced by the number of publications which emerged in 2021. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Related Products of 19064-65-4
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem