Synthesis of pyridazine derivatives. VIII. Imidazo[1,2-b]pyridazines and some tricyclic aza analogs was written by Stanovnik, B.;Tisler, Miha. And the article was included in Tetrahedron in 1967.Reference of 13493-79-3 This article mentions the following:
6-Substituted and 3,6-disubstituted imidazo[1,2-b]pyridazines were prepared Some of these derivatives were used for convenient syntheses of a new azaheterocycle, imidazo[1,2-b]-s-triazolo-[3,4-f]pyridazine (I) and its derivatives Another new heterocyclic system, imidazo [1,2-b]tetrazolo[5,1-f]pyridazine (II) was also prepared 40 references. In the experiment, the researchers used many compounds, for example, 6-Chloroimidazo[1,2-b]pyridazine hydrochloride (cas: 13493-79-3Reference of 13493-79-3).
6-Chloroimidazo[1,2-b]pyridazine hydrochloride (cas: 13493-79-3) belongs to pyridazine derivatives. Pyridazines is a six-membered nitrogen-containing significant heterocycle. It has received considerable interest because of its useful applications as natural products, pharmaceuticals, and various bioactive molecules. The unsubstituted pyridazines are more resistant to eletrophilic substitution due to the nature of withdrawal of electron density from the ring by two heteroatoms, while the related electron deficiency of the ring makes pyridazine more easily attacked by nucleophiles.Reference of 13493-79-3
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem