Model Studies toward the Total Synthesis of Thebaine by an Intramolecular Cycloaddition Strategy was written by Koukal, Petr;Hajicek, Josef;Gupta, Setu;Hudlicky, Tomas. And the article was included in ChemistrySelect in 2017.Related Products of 19064-65-4 This article mentions the following:
Three model compounds required for an approach to thebaine by intramol. [4+2] cycloaddition were prepared In the first two cases the anticipated cycloaddition products were obtained under thermal conditions. Thermolysis of the third, more advanced model compound, afforded products resulting from rearrangements and/or elimination. A study of analogous intra- and intermol. reactions using benzofuran as dienophile and various electron-poor and electron-rich dienes (pyridazines, pyranones, Danishefsky diene) was undertaken. In the experiment, the researchers used many compounds, for example, 3-Methoxypyridazine (cas: 19064-65-4Related Products of 19064-65-4).
3-Methoxypyridazine (cas: 19064-65-4) belongs to pyridazine derivatives. Pyridazine-based compounds continued to be a great source of biologically active compounds as evidenced by the number of publications which emerged in 2021. Pyridazine can act as a hydrogen bond acceptor to improve the physicochemical properties of drug molecules by increasing their water solubility, and has a high affinity for complexing with targets due to its dipole moment.Related Products of 19064-65-4
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem