Pyridazines. LXXV. Quaternary and mesoionic s-triazolo[4,3-b]pyridazines was written by Langof, I.;Stanovnik, B.;Tisler, M.. And the article was included in Croatica Chemica Acta in 1975.Application In Synthesis of 6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one This article mentions the following:
The triazolopyridazine I (R1 = MeO) was prepared from I (R1 = Cl) and MeONa. II (R = Ph, R1 = Cl, OH, OMe, R2 = H, X = ClO4; R = H, R1 = OMe, R2 = H, X = iodo; R = Ph, Cl, R1 = R2 = H,; X = ClO4; R = R1 = R2 = Cl, X = ClO4) and III were prepared by quaternization of the triazolopyridazines. II (R = Ph, R1 = Cl, R2 = H, X = iodo) and KOH gave IV. In the experiment, the researchers used many compounds, for example, 6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one (cas: 33050-32-7Application In Synthesis of 6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one).
6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one (cas: 33050-32-7) belongs to pyridazine derivatives. Pyridazines is a six-membered nitrogen-containing significant heterocycle. It has received considerable interest because of its useful applications as natural products, pharmaceuticals, and various bioactive molecules. Specifically, the pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, cardiotonic, vasodilator, antiarrhythmic, and hypocholesterolaemic.Application In Synthesis of 6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem