Amination of 4-nitropyridazine 1-oxides by liquid ammonia-potassium permanganate was written by Tondys, Hanna;Van der Plas, Henk C.. And the article was included in Journal of Heterocyclic Chemistry in 1986.COA of Formula: C5H6N2O This article mentions the following:
Treatment of 4-nitropyridazine 1-oxide, 3-methoxy-6-chloro-4-nitropyridazine 1-oxide or 3,6-dimethoxy-4-nitropyridazine 1-oxide with a solution of KMnO4 in NH3(l) gives in reasonable-to-good yields the corresponding 5-amino-4-nitropyridazine 1-oxides (75%, 54%, and 62%, resp.). 3,6-Dimethoxypyridazine and 3-methoxypyridazine are converted into the corresponding 4-aminopyridazines I [R = R1 = MeO; R = H, R1 = MeO (II)] on treatment with KNH2/NH2(l)/KMnO4 (yield 50 and 22% resp.). In the last-mentioned reaction besides II 3,3′-dimethoxy 4,4′-bipyridazine (23%) was obtained. In the experiment, the researchers used many compounds, for example, 3-Methoxypyridazine (cas: 19064-65-4COA of Formula: C5H6N2O).
3-Methoxypyridazine (cas: 19064-65-4) belongs to pyridazine derivatives. The pyridazine derivatives are mostly present in biologically active compounds and are also present with different pharmacophores. Pyridazine compounds have attracted interest in various fields like medicinal, industrial, and agricultural research as they are used for numerous biological activities and other applications.COA of Formula: C5H6N2O
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem