Electronic spectra of N-heteroaromatic systems. II. Substituted monocyclic azines was written by Mason, S. F.. And the article was included in Journal of the Chemical Society in 1959.Recommanded Product: 3-Methoxypyridazine This article mentions the following:
The visible and ultraviolet absorption spectra of the monocyclic azines and some derivatives have been measured in polar and nonpolar solvents. The n → π bands of the azines are shifted towards the blue region by electron-donating and towards the red region by electron-accepting substituents, while the π → π bands undergo bathochromic shifts with both types of substituent. The shift of the n → π band of an azine on substitution is due primarily to the effect of the substituent on the energy of the lowest unoccupied benzene-like π orbital of the azine. The solvent λmaximum and εmaximum for the n-π band, λmaximum and ψmaximum for the π → π band are given for pyridine, 2-cyano-, 3-cyano-, 4-cyano-, and 2,6-dicyanopyridine, pyrazine, 2-methyl-, 2,5-dimethyl-, 2,3-dimethoxycarbonyl-, 2,3-dicarboxy, and 2-methoxypyrazine, pyridazine, 3-methyl-, 4-methyl-, 3-methoxy-, 4-methoxy-, 3,6-dimethoxy-, and 4,5-dicarboxy-pyridazine, pyrimidine, 2-methoxy-, 4-methoxy-, 5-hydroxy-, 2-methoxycarbonyl-, 2-carboxy-, 4-carboxy-, and 5-carboxypyrimidine, 3,5,6-trimethyl-1,2,4-triazine, 3-amino-1,2,4-triazine, sym-tetrazine, 1,4-dimethyl-, and 1,4-dicarboxy-sym-tetrazine; each in 1 or more solvents, at various pH values. In the experiment, the researchers used many compounds, for example, 3-Methoxypyridazine (cas: 19064-65-4Recommanded Product: 3-Methoxypyridazine).
3-Methoxypyridazine (cas: 19064-65-4) belongs to pyridazine derivatives. The pyridazine structure is also found within the structure of several drugs such as cefozopran, cadralazine, minaprine, pipofezine, and hydralazine. The unsubstituted pyridazines are more resistant to eletrophilic substitution due to the nature of withdrawal of electron density from the ring by two heteroatoms, while the related electron deficiency of the ring makes pyridazine more easily attacked by nucleophiles.Recommanded Product: 3-Methoxypyridazine
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem