Zhang, Min et al. published their research in Youji Huaxue in 2007 | CAS: 33097-39-1

3,6-Difluoropyridazine (cas: 33097-39-1) belongs to pyridazine derivatives. Pyridazines are rare in nature, possibly reflecting the scarcity of naturally occurring hydrazines, common building blocks for the synthesis of these heterocycles. The unsubstituted pyridazines are more resistant to eletrophilic substitution due to the nature of withdrawal of electron density from the ring by two heteroatoms, while the related electron deficiency of the ring makes pyridazine more easily attacked by nucleophiles.Product Details of 33097-39-1

Synthesis and herbicidal activity of 3-(benzyloxy)-6-fluoropyridazine derivatives was written by Zhang, Min;Hu, Fang-Zhong;Zhu, You-Quan;Zou, Xiao-Mao;Liu, Bin;Yang, Hua-Zheng. And the article was included in Youji Huaxue in 2007.Product Details of 33097-39-1 This article mentions the following:

A series of novel 3-(un)substituted benzyloxy-6-fluoropyridazine derivatives was synthesized by a reaction of various benzyl alcs. with 3,6-difluoropyridazine in CH3CN catalyzed by NaOH. Their structures were identified by 1H NMR, IR spectra and elemental anal. Preliminary bioassay showed that all of them possessed herbicidal activity to some extent against Brassica napus (rape) and Echinochloa crus-galli (barnyard grass). Their structure-activity relationship was discussed. In the experiment, the researchers used many compounds, for example, 3,6-Difluoropyridazine (cas: 33097-39-1Product Details of 33097-39-1).

3,6-Difluoropyridazine (cas: 33097-39-1) belongs to pyridazine derivatives. Pyridazines are rare in nature, possibly reflecting the scarcity of naturally occurring hydrazines, common building blocks for the synthesis of these heterocycles. The unsubstituted pyridazines are more resistant to eletrophilic substitution due to the nature of withdrawal of electron density from the ring by two heteroatoms, while the related electron deficiency of the ring makes pyridazine more easily attacked by nucleophiles.Product Details of 33097-39-1

Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem