Crossland, Ingolf published the artcileDihydropyridazines. XII. Stereochemical course of protonation of pyridazine Grignard adducts, Synthetic Route of 7145-60-0, the main research area is pyridazine Grignard adduct conformation.
Three Grignard-pyridazine adducts (I,R = Me3C, R1 = MeO; R = Ph R1 = MeO; R = Me3C, R1 = Me2N) were prepared The chem. shifts and coupling constants of the 3 ring protons of I were determined and compared with the deuterated analogs. The results showed that the proton introduced during hydrolysis assumed a pseudoaxial position and thus was identical with the proton introduced by base-catalyzed exchange of II(R2 = Me3C and Ph).
Acta Chemica Scandinavica (1947-1973) published new progress about pyridazine Grignard adduct conformation. 7145-60-0 belongs to class pyridazine, name is 6-Chloro-N,N-dimethylpyridazin-3-amine, and the molecular formula is C6H8ClN3, Synthetic Route of 7145-60-0.
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem