Matsumoto, Kiyoshi published the artcileSelectivity in consecutive SNAr-dequaternization reactions of chlorodiazines with tertiary amines, Safety of 6-Chloro-N,N-dimethylpyridazin-3-amine, the main research area is dequaternization reaction chloropyrimidine tertiary amine; chloropyrimidine amination tertiary amine; dealkylation tertiary amine amination chlorodiazine; alkylmethylaminodiazine; diazine alkylmethylamino.
Consecutive SNAr-dealkylation reactions of chlorodiazines, such as, 2-chloropyrimidine (I) and 3,6-dichloropyridazine, with tertiary amines took place in a highly selective fashion. Thus, I was treated with Me2N(CH2)7Me in THF at 100° under 8 kbar pressure to give 97% 2-(methyloctylamino)pyrimidine (II) and 2% 2-(dimethylamino)pyrimidine (III).
Synthetic Communications published new progress about Amination. 7145-60-0 belongs to class pyridazine, name is 6-Chloro-N,N-dimethylpyridazin-3-amine, and the molecular formula is C6H8ClN3, Safety of 6-Chloro-N,N-dimethylpyridazin-3-amine.
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem