Bosset, Cyril; Beucher, Helene; Bretel, Guillaume; Pasquier, Elisabeth; Queguiner, Laurence; Henry, Cyril; Vos, Ann; Edwards, James P.; Meerpoel, Lieven; Berthelot, Didier published the artcile< Minisci-Photoredox-Mediated α-Heteroarylation of N-Protected Secondary Amines: Remarkable Selectivity of Azetidines>, Safety of Ethyl 6-chloroimidazo[1,2-b]pyridazine-2-carboxylate, the main research area is Minisci photoredox mediated alpha heteroarylation azetidine; heteroarylation azetidine spirocyclic derivative.
The development of a general, mild, and functional-group-tolerant direct functionalization of N-heteroarenes by C-H functionalization with N-protected amines, including azetidines under Minisci-mediated photoredox conditions, is reported. A broad scope of substituted azetidines, including spirocyclic derivatives, and heterocycles were explored. This reaction enables the production of sp3-rich complex druglike structures in one step from unactivated feedstock amines and heterocycles.
Organic Letters published new progress about Azetidines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 64067-99-8 belongs to class pyridazine, and the molecular formula is C9H8ClN3O2, Safety of Ethyl 6-chloroimidazo[1,2-b]pyridazine-2-carboxylate.
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem