Haider, Norbert; Heinisch, Gottfried; Lassnigg, Doris published their research in Journal of Heterocyclic Chemistry on February 29 ,1988. The article was titled 《Pyridazines. XXXV. Preparation of some novel pyrimido[4,5-c]pyridazine derivatives from 3-(alkylamino)- and 3-(arylamino)-4-pyridazinecarboxamides》.Product Details of 1445-56-3 The article contains the following contents:
Pyrimido[4,5-c]pyridazinediones I (R = Ph, PhCH2; R1R2 = O), pyrimido[4,5-c]pyridazinones II (R = Ph, PhCH2; R3 = H, Me, Et), and dihydropyrimido[4,5-c]pyridazinones I (R = Ph, PhCH2, Me2CH; R1 = H, R2 = Ph, 3-pyridyl) were prepared from 3-chloro-4-pyridazinecarbonitrile III (R4 = Cl) via amino carbonitriles III (R4 = NHR) and amino carboxamides. In addition, III (R4 = NH2) was prepared from III (R4 = Cl), via the tetrazolo[1,5-b]pyridazine IV as the key intermediate.3-Chloropyridazine-4-carbonitrile(cas: 1445-56-3Product Details of 1445-56-3) was used in this study.
3-Chloropyridazine-4-carbonitrile(cas: 1445-56-3) belongs to pyridazine derivatives.The pyridazine derivatives are mostly present in biologically active compounds and are also present with different pharmacophores. Pyridazines are also important because of their utility in synthetic organic chemistry and in physical organic chemistry.There are reports available for the synthesis of pyridazine and their derivatives by using 2-oxoaldehyes.Product Details of 1445-56-3
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem