《Synthesis, reactions, and spectroscopy of 3-benzoyl-6-phenylpyridazines of expected biological activity》 was written by Issac, Yvette A.. Recommanded Product: 40020-05-1 And the article was included in Zeitschrift fuer Naturforschung, B: Chemical Sciences on August 31 ,1999. The article conveys some information:
Oxidative decyanation of α,6-diphenyl-3-pyridazineacetonitrile in MeOH yielded 3-benzoyl-6-phenylpyridazine (I). α,6-Diphenyl-3-pyridazinemethanol was obtained via NaBH4 reduction of I. Reaction of I with NH2OH or its O-alkyl derivatives yields 3-benzoyl-6-phenylpyridazine oxime (II) and alkyloximes, resp. Treatment of II with AcOH/H2SO4 afforded I again and not the rearranged products. Beckmann rearrangement was achieved for II and the corresponding ethyloxime giving solely 3-carboxanilide-6-phenylpyridazine. 4-Benzoyl-3-phenyl-6-chloropyridazine oxime was synthesized from the corresponding ketone. The results came from multiple reactions, including the reaction of 4,6-Dichloro-3-phenylpyridazine(cas: 40020-05-1Recommanded Product: 40020-05-1)
4,6-Dichloro-3-phenylpyridazine(cas: 40020-05-1) belongs to pyridazine. The pyridazine moiety is an important structural feature of various pharmacologically important compounds with activities like antimicrobial, vasodilator, antiarrhythmic, analgesic, anti-inflammatory, antiplatelet, anticancer, antisecretory, antiulcer, antidepressant, neuroleptic, sedative-hypnotic, anticonvulsant, immunosuppressant, cardiotonic, and hypocholesterolaemic. Recommanded Product: 40020-05-1
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem