Turck, Alain; Ple, Nelly; Mojovic, Ljubica; Ndzi, Bruno; Queguiner, Guy; Haider, Norbert; Schuller, Herbert; Heinisch, Gottfried published the artcile< On the metalation of 4-substituted pyridazines>, Recommanded Product: Pyridazin-4-amine, the main research area is pyridazine metalation lithium methylpiperidide.
A series of new pyridazines bearing ortho-directing groups at C-4 (protected/activated amino or carboxylic acid functionalities) was prepared and their metalation with lithium 2,2,6,6-tetramethylpiperidide was studied. Reactions of the ortho-lithiated species thus obtained with aldehydes as electrophiles opens an access to 4,5-disubstituted pyridazines I (R = NHCOCMe3, CONHCMe3, R1 = Me, Ph).
Journal of Heterocyclic Chemistry published new progress about Metalation. 20744-39-2 belongs to class pyridazine, and the molecular formula is C4H5N3, Recommanded Product: Pyridazin-4-amine.
Referemce:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem