With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.20698-04-8,3,6-Diiodopyridazine,as a common compound, the synthetic route is as follows.
Example 29 A mixture of 5.2 parts of 3,6-diiodopyridazine, 3.5 parts of 1-[3-(trifluoromethyl)phenyl]piperazine, 3.2 parts of sodium carbonate and 90 parts of N , N -dimethylacetamide was stirred and heated overnight at 70C. The reaction mixture was poured onto water. The precipitated product was filtered off and crystallized from 2-propanol, yielding 3.2 parts (48%) of 3-iodo-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-pyridazine; mp. 144.6C (compound 202)., 20698-04-8
20698-04-8 3,6-Diiodopyridazine 250383, apyridazine compound, is more and more widely used in various fields.
Reference£º
Patent; JANSSEN PHARMACEUTICA N.V.; EP156433; (1991); B1;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem