The important role of 21778-81-4

As far as I know, this compound(21778-81-4)Reference of 5-Methoxy-1H-indole-2-carbaldehyde can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Acid Catalyzed Synthesis of Spiroindolone Scaffolds by Iso-Pictet-Spengler Spirocyclization and Evaluation of their Antibacterial Activity, published in 2017, which mentions a compound: 21778-81-4, Name is 5-Methoxy-1H-indole-2-carbaldehyde, Molecular C10H9NO2, Reference of 5-Methoxy-1H-indole-2-carbaldehyde.

Acetic acid catalyzed synthesis of new spiroindolones (tetrahydrospiro-γ-carbolines) was achieved in good yield by iso-Pictet Spengler spirocyclization of substituted isotryptamines with isatins. All the compounds were screened for antibacterial activities against S. aureus, E. coli, P. aeruginosa and S. typhi bacteria. The preliminary antibacterial study indicated that compounds bearing halo substituent showed potent inhibitory activity towards S. typhi and P. aeruginosa and moderate activities towards S. aureus and E. coli.

As far as I know, this compound(21778-81-4)Reference of 5-Methoxy-1H-indole-2-carbaldehyde can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem